期刊： PHARMACOTHERAPY, 2023; 43 (8)
The presence of extracorporeal membrane oxygenation (ECMO) in addition to underlying critical illness can affect the pharmacokinetics and pharmacodyna......
期刊： PHARMACOTHERAPY, 2023; 43 (8)
Study Objective: Severe coronavirus disease 2019 (COVID-19) increases the risk of thrombotic complications with unfractionated heparin (UFH) as a comm......
BackgroundVascular endothelial growth factor inhibitors, including tyrosine kinase inhibitors (TKIs) and anti-angiogenics, are first-line therapies fo......
期刊： PHARMACOTHERAPY, 2023; 43 (11)
Precision medicine is a growing field in critical care. Research increasingly demonstrated pharmacogenomic variability to be an important determinant ......
期刊： PHARMACOTHERAPY, 2023; 43 (8)
Antimicrobial stewardship (AMS) programs have been quick to adopt novel molecular rapid diagnostic technologies (mRDTs) for bloodstream infections (BS......
期刊： PHARMACOTHERAPY, 2023; 43 (9)
Following the results observed in the DAPA-HF trial and subsequent FDA approval of dapagliflozin in patients living with heart failure with reduced ej......
期刊： PHARMACOTHERAPY, 2023; 43 (3)
Study Objective: Aspirin (ASA) has demonstrated inconsistent results in primary prevention of cardiovascular disease (CVD). Guidelines are also incons......
期刊： PHARMACOTHERAPY, 2023; 43 (4)
Study objective: We evaluated US Food and Drug Administration labels for drugs approved under the accelerated approval pathway and whether these label......
期刊： PHARMACOTHERAPY, 2023; 43 (7)
Study Objective: The immunosuppressant tacrolimus is a first-line agent to prevent graft rejection following pediatric heart transplant; however, it s......
期刊： PHARMACOTHERAPY, 2023; 43 (1)
Infections of the central nervous system (CNS) are complex to treat and associated with significant morbidity and mortality. Historically, antistaphyl......
期刊： PHARMACOTHERAPY, 2023; 43 (9)
Despite the availability of several classes of antiemetics, postoperative nausea and vomiting (PONV) remains a substantial burden for patients followi......
期刊： PHARMACOTHERAPY, 2023; 43 (12)
Clozapine is an effective antipsychotic medication used for treatment-resistant schizophrenia. However, it is underutilized due to rigorous hematologi......
期刊： PHARMACOTHERAPY, 2023; 43 (4)
Extravasation is the leakage of intravenous solutions into surrounding tissues, which can be influenced by drug properties, infusion techniques, and p......
期刊： PHARMACOTHERAPY, 2023; 43 (8)
Stenotrophomonas maltophilia is an opportunistic pathogen and frequent cause of serious nosocomial infections. Patient populations at greatest risk fo......
