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Exploring the utility of current polygenic scores in capturing resilience

期刊: PSYCHIATRIC GENETICS, 2022; 32 (1)

Although resilience has been identified to be moderately heritable, little is known about the genetic variants involved. While there has not yet been ......

JIF:1.771

Genetics of social anxiety disorder: a systematic review

期刊: PSYCHIATRIC GENETICS, 2022; 32 (2)

Social anxiety disorder (SAD) is a common psychiatric disorder, often associated with avoidant temperament. Research studies have implicated a strong ......

JIF:1.771

Brain differential gene expression and blood cross-validation of a molecular signature of patients with major depressive disorder

期刊: PSYCHIATRIC GENETICS, 2022; 32 (3)

Introduction The agreement between clinicians diagnosing major depressive disorder (MDD) is poor. The objective of this study was to identify a reprod......

JIF:1.771

Genome-wide methylation analysis of early-onset schizophrenia

期刊: PSYCHIATRIC GENETICS, 2022; 32 (6)

ObjectiveSchizophrenia (SCZ) is a debilitating disease with a complex genetic cause in which age at onset may reflect genetic vulnerability. Though th......

JIF:1.771

Influence of 5-HTTLPR polymorphism on postpartum depressive and posttraumatic symptoms

期刊: PSYCHIATRIC GENETICS, 2022; 32 (1)

Introduction Postpartum depression (PPD) is a multifactor disorder caused by psychological, social, and also biological factors. 5-HTTLPR polymorphism......

JIF:1.771

Genome-wide DNA methylation profiles of autism spectrum disorder

期刊: PSYCHIATRIC GENETICS, 2022; 32 (4)

Objectives We aimed to identify differentially methylated genes and related signaling pathways in autism spectrum disorder (ASD). Methods First, the D......

JIF:1.771

Stimulant intolerance in children with Angelman syndrome with hyperactivity: a case series

期刊: PSYCHIATRIC GENETICS, 2022; 32 (2)

Objectives Angelman syndrome is a neurogenetic disorder resulting from the loss of expression of the ubiquitin-protein ligase E3A gene on chromosome 1......

JIF:1.771

A scoping review and comparison of approaches for measuring genetic heterogeneity in psychiatric disorders

期刊: PSYCHIATRIC GENETICS, 2022; 32 (1)

An improved understanding of genetic etiological heterogeneity in a psychiatric condition may help us (a) isolate a neurophysiological 'final common p......

JIF:1.771

Novel RPS6KA3 mutations cause Coffin-Lowry syndrome in two patients and concurrent compulsive eyebrow-pulling behavior in one of them

期刊: PSYCHIATRIC GENETICS, 2022; 32 (5)

Coffin-Lowry syndrome (CLS) is a rare X-linked disorder that, usually affects males, presenting with intellectual disability, short stature, growth re......

JIF:1.771

Evaluation of hsa-let-7d-5p, hsa-let-7g-5p and hsa-miR-15b-5p plasma levels in patients with Alzheimer's disease

期刊: PSYCHIATRIC GENETICS, 2022; 32 (1)

Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder MicroRNAs (miRNAs) may be promising diagnostic biomarkers for AD. Prev......

JIF:1.771

Mendelian randomization study on the effect of tumor necrosis factor on schizophrenia

期刊: PSYCHIATRIC GENETICS, 2022; 32 (6)

ObjectivePrevious observational studies have shown that the levels of tumor necrosis factor (TNF) increased in patients with schizophrenia. The presen......

JIF:1.771

Morphine may have a role in telomere shortening

期刊: PSYCHIATRIC GENETICS, 2022; 32 (2)

Morphine/heroin may increase oxidative stress in drug-dependent persons. The imbalance between oxidative stress and antioxidant defense mechanisms can......

JIF:1.771

Treatment-resistant manic episode in a patient diagnosed with bipolar affective disorder

期刊: PSYCHIATRIC GENETICS, 2022; 32 (6)

A considerable group of patients suffering from mental health disorders do not respond adequately to pharmacological treatment. For the purposes of pr......

JIF:1.771

Identification of rare mutations of the vasoactive intestinal peptide receptor 2 gene in schizophrenia

期刊: PSYCHIATRIC GENETICS, 2022; 32 (3)

Objective Studies showed that rare copy number variations (CNVs) encompassing the vasoactive intestinal peptide receptor 2 gene (VIPR2) were associate......

JIF:1.771

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