期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 140 ()
In this study, the toxicity of ferric oxide nanoparticles (Fe2O3 NPs) administered through gavage to Sprague Dawley (SD) rats for 94 d, consecutively ......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 141 ()
The TTC (Threshold of Toxicological Concern; set at 1.5 mu g/day for pharmaceuticals) defines an acceptable patient intake for any unstudied chemical ......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 142 ()
A new IUCLID database is provided containing results from non-clinical animal studies and human information for 530 approved drugs. The database was d......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 144 ()
One of the most widely used herbicides worldwide, glyphosate is registered for use in many agricultural and non agricultural settings. Accordingly, re......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 144 ()
Propylene dichloride (PDC) is a chlorinated substance used primarily as an intermediate in basic organic chemical manufacturing. The United States Env......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 145 ()
The toxicokinetics of manganese (Mn) are controlled through homeostasis because Mn is an essential element. However, at elevated doses, Mn is also neu......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 137 ()
Inhalation is a critical route for occupational exposure. To protect workers from adverse effects, health-based exposure limits (HBELs) are derived us......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 142 ()
China is the world's largest consumer of cigarettes. However, the potential cancer risk posed by polycyclic aromatic hydrocarbons (PAHs) in mainstream......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 142 ()
In rats, hypothyroidism during fetal and neonatal development can disrupt neuronal migration and induce the formation of periventricular heterotopia i......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 143 ()
Hazard classification and risk assessment of substances, is essential to protect workers and consumers from hazardous substances including reproductiv......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 144 ()
Local and systemic contamination caused by metal ions leaching from medical device materials is a significant and continuing health problem. The incre......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 137 ()
In silico models are often built solely on publicly available data which may mean that they are less predictive for proprietary chemical space. Data s......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 138 ()
The extent and rigor of peer review that a model undergoes during and after development influences the con-fidence of users and managers in model pred......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 141 ()
Propranolol is a widely used & beta;-blocker that can generate a nitrosated derivative, N-nitroso propranolol (NNP). NNP has been reported to be n......
期刊： REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023; 142 ()
We present a case study for afidopyropen (AF; insecticide) to characterize chronic dietary human health risk using a Risk 21-based approach. Our objec......
