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Mice 3D testicular organoid system as a novel tool to study Zika virus pathogenesis

期刊: VIROLOGICA SINICA, 2023; 38 (1)

Zika virus (ZIKV) poses a serious threat to global public health due to its close relationship with neurological and male reproductive damage. However......

Omicron variants breakthrough infection elicited higher specific memory immunity than third dose booster in healthy vaccinees

期刊: VIROLOGICA SINICA, 2023; 38 (2)

Homologous booster, heterologous booster, and Omicron variants breakthrough infection (OBI) could improve the humoral immunity against Omicron variant......

Transcriptome analysis of CD4+T cells from HIV-infected individuals receiving ART with LLV revealed novel transcription factors regulating HIV-1 promoter activity

期刊: VIROLOGICA SINICA, 2023; 38 (3)

Some HIV-infected individuals receiving ART develop low-level viremia (LLV), with a plasma viral load of 50-1000 copies/mL. Persistent low-level virem......

Autophagy induced by human adenovirus B7 structural protein VI inhibits viral replication

期刊: VIROLOGICA SINICA, 2023; 38 (5)

Human adenovirus B7 (HAdV-B7) causes severe acute lower respiratory tract infections in children. However, neither the child-specific antivirals or va......

Equine ANP32 proteins support influenza A virus RNA polymerase activity

期刊: VIROLOGICA SINICA, 2023; 38 (6)

Host ANP32 family proteins are crucial for maintaining the activity of influenza RNA polymerase and play an important role in the cross-species transm......

Epidemiology and genetic diversity of norovirus GII genogroups among children in Hubei, China, 2017-2019

期刊: VIROLOGICA SINICA, 2023; 38 (3)

Norovirus (NoV) is an important cause of viral acute gastroenteritis (AGE). To gain insights into the epidemio-logical characteristics and genetic div......

RIPK3 promotes hantaviral replication by restricting JAK-STAT signaling without triggering necroptosis

期刊: VIROLOGICA SINICA, 2023; 38 (5)

Hantaan virus (HTNV) is a rodent-borne virus that causes hemorrhagic fever with renal syndrome (HFRS), resulting in a high mortality rate of 15%. Inte......

Changing predominance of norovirus strains in children with acute gastroenteritis in Shanghai, 2018-2021

期刊: VIROLOGICA SINICA, 2023; 38 (5)

Norovirus (NoV) is a major pathogen that causes acute gastroenteritis (AGE) in people of all ages, especially in children. In this study, we investiga......

Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding

期刊: VIROLOGICA SINICA, 2023; 38 (4)

The Dicistroviridae is a virus family that includes many insect pathogens. These viruses contain a positive-sense RNA genome that is replicated by the......

Abnormal liver function in children hospitalized with acute respiratory infection of adenoviruses: a retrospective study

期刊: VIROLOGICA SINICA, 2023; 38 (5)

Human adenoviruses (HAdVs) can cause acute hepatitis in immunocompromised patients. However, it is unclear whether HAdVs are contributors to hepatitis......

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