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Immune-Related Adverse Events Mimicking Behcet's Disease in a Gastric Cancer Patient Following Camrelizumab Treatment

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2020; 17 (2)

Background: Anti-programmed cell death 1(anti-PD-1) antibodies are immune checkpoint inhibitors (ICIs) used as a treatment option for a number of canc......

The Changes of Th17 Cytokines Expression and Its Correlation with Receptor Activator of Nuclear Factor Kappa B Ligand During Orthodontic Tooth Movement

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2020; 17 (2)

Background: IL-17 is reported to be associated with the pathophysiology of Orthodontic Tooth Movement (OTM) by affecting osteoclastogenesis. Objective......

Effects of Long-Time Exposure to Lipopolysaccharide on Intestinal Lymph Node Immune Cells and Antibodies Level in Mice

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2020; 17 (3)

Background: Endotoxin, widely present in the living environment of humans and animals, leads to endotoxemia during a short period. However, the long-t......

IL-6 and IL-10 Closely Correlate with Bacterial Bloodstream Infection

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2020; 17 (3)

Background: Given the high mortality of bacterial bloodstream infections (BSI), blood culture results do not meet clinical needs timely due to being t......

Reno-Protective Effect of Realgar Nanoparticles on Lupus Nephritis of MRL/Lpr Mice through STAT1

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2019; 16 (2)

Background: Realgar, an arsenic tetrasulfide compound, is a highly recognized traditional Chinese medicinal prescription that has been widely used to ......

JIF:0.94

The Effect of Entecavir Therapy on Immune Status in Chronic Hepatitis B Patients

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2019; 16 (1)

Background: Entecavir (ETV) is an antiviral medication effective in suppressing hepatitis B virus (HBV) replication and improving liver function. Howe......

JIF:0.94

Increased Serum Levels of Soluble B7-H4 in Patients with Systemic Lupus Erythematosus

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2019; 16 (1)

Background: Members of B7 family are reported to regulate lymphocytes activation, transmit both costimulatory and co-inhibitory signals, control T cel......

JIF:0.94

All-trans Retinoic Acid Regulates the Balance of Treg-Th17 Cells through ERK and P38 Signaling Pathway

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2019; 16 (1)

Background: All-trans retinoic acid (ATRA) potentiates TGF-beta-dependent regulatory T cells (Treg) induction, while it inhibits pro-inflammatory inte......

JIF:0.94

Hepcidin Induces M1 Macrophage Polarization in Monocytes or THP-1 Derived Macrophages

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2019; 16 (3)

Background: Macrophage polarization plays a critical role in determining the inflammatory states. Hepcidin is a key negative regulator of iron homeost......

JIF:0.94

Identification of hnRNP C1/C2 as an Autoantigen in Patients with Behcet's Disease

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2018; 15 (2)

Background: Ribonucleoproteins particles that form the spliceosomes are among the most frequently targeted molecules of the autoimmune response. In th......

JIF:0.94

Hemin Induces the Activation of NLRP3 Inflammasome in N9 Microglial Cells

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2018; 15 (2)

Background: Hemin is an important sterile component that induces a neuroinflammatory response after intracerebral hemorrhage, in which NLRP3 inflammas......

JIF:0.94

Association between KIR Genes and Efficacy of Treatment of HBeAg-Positive Chronic Hepatitis B Patients with Entecavir

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2018; 15 (2)

Background: Entecavir (ETV) is commonly used to treat chronic hepatitis B (CHB) in China. However, certain percentages of e-Antigen (HBeAg) positive C......

JIF:0.94

Anti-inflammatory Effects of PMX205 in Mouse Macrophage Periodontitis Model

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2018; 15 (2)

Background: C5areceptor antagonistPMX205 is a synthetic hexapeptidecapable of blocking C5a-C5a receptor (C5aR) axis by simulating C5a active C-termina......

JIF:0.94

Soluble CD163 Levels and CD163+CD14+Monocyte/Macrophage Counts in Patients with Asthma

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2018; 15 (3)

Background: CD163-expressing macrophages are involved in the inflammatory response in asthma. Objective: To assess sputum and serum soluble CD163 (sCD......

JIF:0.94

The Soluble and Particulate Form of Alginates Positively Regulate Immune Response

期刊: IRANIAN JOURNAL OF IMMUNOLOGY, 2018; 15 (3)

Background: Alginate materials have been widely employed for biomedical applications ranging from wound healing to cancer treatment. However, how algi......

JIF:0.94

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