期刊： EPIGENETICS & CHROMATIN, 2022; 15 (1)
Background Although paternal exposure to cigarette smoke may contribute to obesity and metabolic syndrome in offspring, the underlying mechanisms rema......
期刊： EPIGENETICS & CHROMATIN, 2022; 15 (1)
The cause of nuclear shape abnormalities which are often seen in pre-neoplastic and malignant tissues is not clear. In this study we report that defor......
期刊： EPIGENETICS & CHROMATIN, 2022; 15 (1)
Background Heterosis of growth traits in allotriploid fish has benefited the production of aquaculture for many years, yet its genetic and molecular b......
期刊： EPIGENETICS & CHROMATIN, 2021; 14 (1)
Histone chaperones facilitate DNA replication and repair by promoting chromatin assembly, disassembly and histone exchange. Following histones synthes......
期刊： EPIGENETICS & CHROMATIN, 2021; 14 (1)
Background Although extrachromosomal DNA (ecDNA) has been intensively studied for several decades, the mechanisms underlying its tumorigenic effects h......
期刊： EPIGENETICS & CHROMATIN, 2021; 14 (1)
Background Delta Np63 is a master transcriptional regulator playing critical roles in epidermal development and other cellular processes. Recent studi......
期刊： EPIGENETICS & CHROMATIN, 2021; 14 (1)
Splicing factors have recently been shown to be involved in heterochromatin formation, but their role in controlling heterochromatin structure and fun......
期刊： EPIGENETICS & CHROMATIN, 2021; 14 (1)
Background: Maternal protein restriction diet (PRD) increases the risk of metabolic dysfunction in adulthood, the mechanisms during the early life of ......
期刊： EPIGENETICS & CHROMATIN, 2021; 14 (1)
Histone crotonylation is a recently described post-translational modification that occurs at multiple identified histone lysine crotonylation sites. A......
期刊： EPIGENETICS & CHROMATIN, 2020; 13 (1)
Background Chromatin physical interactions provide essential information for understanding the regulation ofcis-elements like enhancers, promoters, an......
期刊： EPIGENETICS & CHROMATIN, 2020; 13 (1)
Background H2A.B, the most divergent histone variant of H2A, can significantly modulate nucleosome and chromatin structures. However, the related stru......
期刊： EPIGENETICS & CHROMATIN, 2020; 13 (1)
Background DNA methylation, as an essential epigenetic modification found in mammals and plants, has been implicated to play an important role in inse......
期刊： EPIGENETICS & CHROMATIN, 2020; 13 (1)
Polycomb repressive complex 2 (PRC2) is a chromatin-modifying enzyme that catalyses the methylation of histone H3 at lysine 27 (H3K27me1/2/3). This co......
期刊： EPIGENETICS & CHROMATIN, 2020; 13 (1)
With the rapid development of next-generation sequencing technology, chromosome structural variation has gradually gained increased clinical significa......
期刊： EPIGENETICS & CHROMATIN, 2020; 13 (1)
Background An increasing number of nucleic acid modifications have been profiled with the development of sequencing technologies. DNA N-6-methyladenin......
