Clonal hematopoiesis driven by DNMT3A and TET2 mutations: role in monocyte and macrophage biology and atherosclerotic cardiovascular disease

期刊： CURRENT OPINION IN HEMATOLOGY, 2022; 29 (1)

Purpose of review Clonal hematopoiesis of indeterminate potential (CHIP), defined by the presence of somatic mutations in hematopoietic cells, is asso......

JIF：2.769

Update on preclinical and clinical efforts on ex-vivo expansion of hematopoietic stem and progenitor cells

期刊： CURRENT OPINION IN HEMATOLOGY, 2022; 29 (4)

Purpose of review Ex-vivo expansion of hematopoietic stem cells (HSCs) is one potential approach to enhance the clinical efficacy of hematopoietic cel......

JIF：2.769

Prothrombotic state associated with preeclampsia

期刊： CURRENT OPINION IN HEMATOLOGY, 2021; 28 (5)

Purpose of review Preeclampsia is a common complication of pregnancy and contributes significantly to maternal and fetal morbidity and mortality. A pr......

Mechanisms of failure of chimeric antigen receptor T-cell therapy

期刊： CURRENT OPINION IN HEMATOLOGY, 2019; 26 (6)

Purpose of review Although chimeric antigen receptor T (CART)-cell therapy is best recognized for its antitumor effect in relapsed/refractory B-cell h......

JIF：2.86

Mitochondrial metabolism and the maintenance of hematopoietic stem cell quiescence

期刊： CURRENT OPINION IN HEMATOLOGY, 2019; 26 (4)

Purpose of review Hematopoietic stem cells (HSCs) are characterized by a potent multilineage regenerative capability that is dependent on their quiesc......

JIF：2.86

Microtransplantation: clinical applications and mechanisms

期刊： CURRENT OPINION IN HEMATOLOGY, 2018; 25 (6)

Purpose of review Microtransplantation (MST) has been successfully used to manage patients with hematological malignancies, especially older patients ......

JIF：2.86