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Identification of Isthmin1 in the small annual fish, Nothobranchius guentheri, as a novel biomarker of aging and its potential rejuvenation activity

期刊: BIOGERONTOLOGY, 2022; 23 (1)

Isthmin 1 (Ism1) has been shown to play roles in multiple biological processes including morphogenesis, hematopoiesis, antiviral immune response and s......

JIF:3.743

Dietary intake of diosgenin delays aging of male fish Nothobranchius guentheri through modulation of multiple pathways that play prominent roles in ROS production

期刊: BIOGERONTOLOGY, 2022; 23 (2)

Oxidative stress including DNA damage, increased lipid and protein oxidation, is an important feature of aging. Diosgenin (DG) has been shown to have ......

JIF:3.743

Handelin extends lifespan and healthspan of Caenorhabditis elegans by reducing ROS generation and improving motor function

期刊: BIOGERONTOLOGY, 2022; 23 (1)

Aging and aging-related disorders contribute to formidable socioeconomic and healthcare challenges. Several promising small molecules have been identi......

JIF:3.743

Dietary intake of GDF11 delays the onset of several biomarkers of aging in male mice through anti-oxidant system via Smad2/3 pathway

期刊: BIOGERONTOLOGY, 2022; 23 (3)

Current studies have generated controversy over the age-related change in concentration of growth differentiation factor 11 (GDF11) and its role in th......

JIF:3.743

Tackling cellular senescence by targeting miRNAs

期刊: BIOGERONTOLOGY, 2022; 23 (4)

Cellular senescence, which is characterized by permanent proliferation arrest, has become an important target for the amelioration of various human di......

JIF:3.743

Ginseng volatile oil prolongs the lifespan and healthspan of Caenorhabditis elegans

期刊: BIOGERONTOLOGY, 2022; 23 (4)

Ginseng volatile oil (GVO) is one of the main components of ginseng and has antibacterial and anti-inflammatory properties. In this study, gas chromat......

JIF:3.743

The role of NAD and NAD precursors on longevity and lifespan modulation in the budding yeast, Saccharomyces cerevisiae

期刊: BIOGERONTOLOGY, 2022; 23 (2)

Molecular causes of aging and longevity interventions have witnessed an upsurge in the last decade. The resurgent interests in the application of smal......

JIF:3.743

Aging and age-related diseases: from mechanisms to therapeutic strategies

期刊: BIOGERONTOLOGY, 2021; 22 (2)

Aging is a physiological process mediated by numerous biological and genetic pathways, which are directly linked to lifespan and are a driving force f......

Metformin prevents against oxidative stress-induced senescence in human periodontal ligament cells

期刊: BIOGERONTOLOGY, 2020; 21 (1)

Periodontitis is a chronic infectious disease involving periodontal tissues. Periodontal ligament cells (PDLCs) play an important role in the regenera......

d-Galactose-induced oxidative stress and mitochondrial dysfunction in the cochlear basilar membrane: an in vitro aging model

期刊: BIOGERONTOLOGY, 2020; 21 (3)

The cochlear basilar membrane (CBM) contains inner hair cells and outer hair cells that convert sound waves into electrical signals and transmit them ......

17 beta-estradiol inhibits H2O2-induced senescence in HUVEC cells through upregulating SIRT3 expression and promoting autophagy

期刊: BIOGERONTOLOGY, 2020; 21 (5)

17 beta-estradiol (17 beta-E-2) has been implicated in inhibiting the senescence of vascular endothelial cells (VEC) and slowing down the process of a......

Coix seed oil prolongs lifespan and enhances stress resistance in Caenorhabditis elegans

期刊: BIOGERONTOLOGY, 2020; 21 (2)

Coix seed oil (CSO) has many beneficial effects, but there is limited research on its influence on the processes and mechanisms related to senescence.......

Sirtuins family as a target in endothelial cell dysfunction: implications for vascular ageing

期刊: BIOGERONTOLOGY, 2020; 21 (5)

The vascular endothelium is a protective barrier between the bloodstream and the vasculature that may be disrupted by different factors such as the pr......

Functional alterations and transcriptomic changes during zebrafish cardiac aging

期刊: BIOGERONTOLOGY, 2020; 21 (5)

Aging dramatically increases the risk of cardiovascular diseases in human. Animal models are of great value to study cardiac aging, and zebrafish have......

Tectochrysin increases stress resistance and extends the lifespan of Caenorhabditis elegans via FOXO/DAF-16

期刊: BIOGERONTOLOGY, 2020; 21 (5)

Aging is related to the lowered overall functioning and increased risk for various age-related diseases in humans. Tectochrysin is a flavonoid compoun......

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