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UBR5 promotes migration and invasion of glioma cells by regulating the ECRG4/NF-kappa B pathway

期刊: JOURNAL OF BIOSCIENCES, 2022; 47 (3)

Human glioma is a kind of common and fatal intracranial tumor. Therefore, exploring effective drug targets for glioma is the main task of basic and cl......

JIF:1.498

E2F1-mediated up-regulation of TOP2A promotes viability, migration, and invasion, and inhibits apoptosis of gastric cancer cells

期刊: JOURNAL OF BIOSCIENCES, 2022; 47 (4)

Previous studies have reported that E2F transcription factor 1 (E2F1) and DNA topoisomerase II alpha (TOP2A) are up-regulated in gastric cancer (GC), ......

JIF:1.498

Circ-WDR27 regulates mycobacterial vitality and secretion of inflammatory cytokines in Mycobacterium tuberculosis-infected macrophages via the miR-370-3p/FSTL1 signal network

期刊: JOURNAL OF BIOSCIENCES, 2022; 47 (2)

Tuberculosis (TB) is a common disease caused by Mycobacterium tuberculosis (M.tb) infection. Our study was to explore the function and mechanism of ci......

JIF:1.498

Inhibition of autophagy impairs free fatty acid-induced excessive lipid accumulation in hepatocellular carcinoma and hepatic cells

期刊: JOURNAL OF BIOSCIENCES, 2022; 47 (2)

Autophagy is a reparative life-sustaining process. Dysfunctions of autophagy play an important role in the progression of chronic liver diseases. The ......

JIF:1.498

Pelargonidin inhibits vascularization and metastasis of brain gliomas by blocking the PI3K/AKT/mTOR pathway

期刊: JOURNAL OF BIOSCIENCES, 2022; 47 (4)

Pelargonidin has attracted much attention in many cancers. Whether the growth of glioma inhibited by pelargonidin is related to the PI3K/AKT/mTOR path......

JIF:1.498

circRERE regulates the expression of GBX2 through miR-1299 and ZC3H13/N-6-methyladenosine (m(6)A) to promote growth and invasion of hepatocellular carcinoma cells

期刊: JOURNAL OF BIOSCIENCES, 2022; 47 (3)

Hepatocellular carcinoma (HCC) is one of the most common malignant tumours in the world. Current studies have shown that circular RNAs (circRNAs) and ......

JIF:1.498

A Kazal-type serine protease inhibitor mediates innate immunity in wild silkworm Actias selene Hubner

期刊: JOURNAL OF BIOSCIENCES, 2022; 47 (2)

The prophenoloxidase (PPO) activation system is an important innate immune defense mechanism in arthropods. Actias selene is a rare and important wild......

JIF:1.498

SMYD3 regulates the abnormal proliferation of non-small-cell lung cancer cells via the H3K4me3/ANO1 axis

期刊: JOURNAL OF BIOSCIENCES, 2022; 47 (3)

Non-small-cell lung cancer (NSCLC) is the most prevalent type of lung cancer. This study evaluated the mechanism of histone methyltransferase SET and ......

JIF:1.498

CircRNA expression profiling and bioinformatics analysis indicate the potential biological role and clinical significance of circRNA in influenza A virus-induced lung injury

期刊: JOURNAL OF BIOSCIENCES, 2021; 46 (2)

Circular RNA (circRNA) plays an important role in the regulation of multiple biological processes. However, circRNA profiling and the potential biolog......

MRTF-A regulates Ca2+ release through CACNA1S

期刊: JOURNAL OF BIOSCIENCES, 2021; 46 (2)

Gene therapy is considered a potential treatment for Duchenne muscular dystrophy (DMD). Researchers have been working on this for many years to find e......

Exploration of wheat yellow mosaic virus-responsive miRNAs and their targets in wheat by miRNA and degradome sequencing

期刊: JOURNAL OF BIOSCIENCES, 2021; 46 (3)

Wheat (Triticum aestivum) is one of the most important food crops around the world. China is the largest wheat production country and wheat yellow mos......

Prognostic value and immunological characteristics of a novel autophagy-related signature in pancreatic cancer

期刊: JOURNAL OF BIOSCIENCES, 2021; 46 (3)

Autophagy affects the development, progression, and prognosis of various cancers including pancreatic cancer. To develop an autophagy-related prognost......

S100A9-containing serum exosomes of burn injury patients promote permeability of pulmonary microvascular endothelial cells

期刊: JOURNAL OF BIOSCIENCES, 2021; 46 (2)

Microvascular hyperpermeability is a leading mechanism responsible for occurrence of edema in remote organs and tissues in patients with burn injury. ......

N-3-(oxododecanoyl)-l-homoserine lactone suppresses dendritic cell maturation by upregulating the long noncoding RNA NRIR

期刊: JOURNAL OF BIOSCIENCES, 2021; 46 (3)

N-3-(oxododecanoyl)-l-homoserine lactone (3-O-C12-HSL), a small bacterial signaling molecule secreted by Pseudomonas aeruginosa (P. aeruginosa), can b......

Knockdown of circ_0008344 contributes to radiosensitization in glioma via miR-433-3p/RNF2 axis

期刊: JOURNAL OF BIOSCIENCES, 2021; 46 (3)

Numerous studies have identified that circular RNAs (circRNAs) functioned as important regulators in tumor initiation, carcinogenesis, drug or radiati......

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