期刊: BIOSTATISTICS, 2021; 22 (2)
Inferring brain connectivity network and quantifying the significance of interactions between brain regions are of paramount importance in neuroscienc......
期刊: BIOSTATISTICS, 2021; 22 (1)
When the primary outcome is difficult to collect, a surrogate endpoint is typically used as a substitute. It is possible that for every individual, th......
期刊: BIOSTATISTICS, 2020; 21 (4)
Alzheimer's disease (AD) is a chronic neurodegenerative disease that changes the functional connectivity of the brain. The alteration of the strong co......
期刊: BIOSTATISTICS, 2019; 20 (1)
When a single gene influences more than one trait, known as pleiotropy, it is important to detect pleiotropy to improve the biological understanding o......
期刊: BIOSTATISTICS, 2017; 18 (4)
In multivariate longitudinal HIV/AIDS studies, multi-outcome repeated measures on each patient over time may contain outliers, and the viral loads are......
期刊: BIOSTATISTICS, 2017; 18 (1)
Under the framework of Bayesian model selection, we propose a nonparametric overdose control (NOC) design for dose finding in phase I clinical trials.......
期刊: BIOSTATISTICS, 2022; 23 (3)
Growing evidence has shown that the brain connectivity network experiences alterations for complex diseases such as Alzheimer's disease (AD). Network ......
期刊: BIOSTATISTICS, 2022; 23 (2)
In recent biomedical research, genome-wide association studies (GWAS) have demonstrated great success in investigating the genetic architecture of hum......
期刊: BIOSTATISTICS, 2022; 23 (1)
We develop methods for assessing the predictive accuracy of a given event time model when the validation sample is comprised of case K interval-censor......
期刊: BIOSTATISTICS, 2022; 23 (3)
The main challenge in cancer genomics is to distinguish the driver genes from passenger or neutral genes. Cancer genomes exhibit extensive mutational ......