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Bioactive Compounds of Polygonatum sibiricum-Therapeutic Effect and Biological Activity

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (1)

Plants serve as an important source of medicinal compounds, and their use in various diseases dates back hundreds of years. One such plant-based compo......

Thyroid Diseases During Pregnancy: Bibliometric Analysis of Scientific Publications

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (2)

Background: Bibliometric analysis can analyze development trends and predict research hotspots. We used these analyses to better understand the pregna......

Ginsenoside Rg1 Attenuates Premature Ovarian Failure of D-gal Induced POF Mice Through Downregulating p16INK4a and Upregulating SIRT1 Expression

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (3)

Background: Premature ovarian failure (POF) refers to pathological amenorrhea before 40 years. Objective: To explore the regulatory effect of Rg1 on P......

Therapeutic Effects and Mechanism of Liraglutide in Rats with Type 2 Diabetes and Metabolic-associated Fatty Liver Disease

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (9)

Background: SREBP-1c/Insig/SCAP acts as a lipid de novo synthesis pathway, and its factors are highly expressed in the endoplasmic reticulum. At prese......

Cortex Mori Radicis Attenuates Streptozotocin-induced Diabetic Renal Injury in Mice via Regulation of Transient Receptor Potential Canonical Channel 6

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (8)

Objective: Cortex Mori Radicis (CMR) has been reported to possess antipyretic, anti-convulsant, anti-allergic, anti-inflammatory, and anti-diabetic ef......

Inflammasomes as Potential Therapeutic Targets in Atherosclerotic Cardiovascular Disease

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (14)

Recent studies have shown that interleukin 1 beta monoclonal antibody improves the prognosis of patients with coronary artery disease independently of......

Probiotic Properties of a Spaceflight-induced Mutant Lactobacillus Plant-arum SS18-50 in Mice

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (5)

Background: Probiotics are a group of bacteria that play a critical role in intestinal microbiota homeostasis and may help adjunctively treat certain ......

Susceptibility of Glutathione-S-Transferase Polymorphism to CVD Develo-pment in Type 2 Diabetes Mellitus-A Review

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (2)

Metabolic disorder affects normal homeostasis and can lead to the development of diseases. Diabetes mellitus is the most common metabolic disorder, an......

The Emerging Roles of IL-36, IL-37, and IL-38 in Diabetes Mellitus and its Complications

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (10)

Diabetes mellitus is a metabolic disease caused by a combination of genetic and environmental factors. The importance of the inflammatory response occ......

Impact of RET Screening on the Management of Multiple Endocrine Neoplasia Type 2A: 10 Years Experience and Follow-Up in Three Families

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (3)

Background: Multiple endocrine neoplasia type 2A (MEN 2A) is mainly caused by germline RET codon C634 mutation and is characterized by Medullary Thyro......

Adiponectin is Inversely Associated with Insulin Resistance in Adolescents with Nonalcoholic Fatty Liver Disease

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (6)

Background: Insulin Resistance (IR) is confirmed as a key feature of Nonalcoholic Fatty Liver Disease (NAFLD) in children and adolescents. Numerous st......

Pathogenic Roles of m6A Modification in Viral Infection and Virus-driven Carcinogenesis

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (10)

N6-methyladenosine (m6A) is a prevalent modification of RNA in eukaryotes, bacteria, and viruses. It is highly conserved and can affect the structure,......

Inhibiting TLR9 Signaling Stimulates Apoptosis and Cell Cycle Arrest, and Alleviates Angiogenic Property in Human Cervical Cancer Cells

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022; 22 (5)

Aims: The aim of the study was to assess the effect of blocking TLR9 signaling on the proliferation of cervical cancer cells and its angiogenic proper......

Hidden Hunger of Vitamin E Among Healthy College Students: A Cross-Sectional Study

期刊: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2021; 21 (6)

Background: College students may have a risk of fat-soluble vitamin deficiencies due to unhealthy dietary habits, especially for vitamin A and E. They......

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