筛选条件 共查询到160条结果
排序方式
MiR-1179 is downregulated in cervical cancer and its overexpression suppresses cancer cells invasion by targeting CHAF1A/ZEB1

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

The anticancer effect of miR-1179 has been extensively studied in many tumors. The mechanism of miR-1179 action in cervical cancer, however, remains l......

ARF3 inhibits proliferation and promotes apoptosis in gastric cancer by regulating AKT and ERK pathway

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

ADP-ribosylation factor 3 (ARF3) has confirmed participate in diverse biological processes in many cancers. However, the expression patterns and roles......

miR-19a-3p inhibition alleviates sepsis-induced lung injury via enhancing USP13 expression

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

Sepsis is a systemic inflammatory response syndrome caused by various pathogenic microorganisms or toxins. Lung damage is one of the causes of death i......

Inhibition of GPR4 attenuates SH-SY5Y cell injury in cerebral ischemia/reperfusion via anti-apoptotic pathways

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

Cerebral ischemia/reperfusion injury (CIRI) can lead to increased vascular endothelial permeability and blood-brain barrier damage in patients with st......

Ononin induces cell apoptosis and reduces inflammation in rheumatoid arthritis fibroblast-like synoviocytes by alleviating MAPK and NF-kappa B signaling pathways

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

As a kind of chronic inflammatory diseases, rheumatoid arthritis (RA) has a low cure rate and easy recurrence. It has widely reported that abnormal ac......

Meisoindigo inhibits cellular proliferation via down-regulation of the PI3K/Akt pathway and induces cellular apoptosis in glioblastoma U87 cells

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

Objective: The current study was to explore whether meisoindigo was effective in suppressing proliferation and inducing apoptosis of human glioblastom......

The upregulation of miR-204-3p in LPS-induced acute lung injury aggravated pulmonary endothelial cells apoptosis via targeting sulfatase 2

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

Acute lung injury (ALI) results from the injury of alveolar epithelial cells and pulmonary capillary endothelial cells, with a high mortality rate ran......

MiR-490 alleviates sepsis-induced acute lung injury by targeting MRP4 in new-born mice

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

The aim of this study was to investigate whether the effects of miR- 490 on acute lung injury (ALI) induced by sepsis in vitro and in vivo were throug......

Upregulation of miR-1266-5p serves as a prognostic biomarker of hepatocellular carcinoma and facilitates tumor cell proliferation, migration and invasion

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

Objective: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. This study aimed to analyze the prognostic v......

Abnormal expression of FAK and paxillin correlates with oral cancer invasion and metastasis

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

Globally, the tenth most common cancer is the oral squamous cell carcinoma (OSCC) and the treatment strategy for improving of OSCC patients survival r......

Overexpression of miR-874-3p alleviates LPS-induced apoptosis and inflammation in alveolar epithelial cell by targeting EGR3/NF-kappa B

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

Objective: MicroRNA (miRNA) is implicated in the pathogenic mechanism of pneumonia. Role of miR-874-3p in pediatric pneumonia was therefore evaluated ......

Clinical significance of cancer stem cell markers in lung carcinoma

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

The identification of side population (SP) cells in several cancer studies has been proved to be involved in the treatment failure (chemotherapy) and ......

LncRNA UCA1 alleviates aberrant hippocampal neurogenesis through regulating miR-375/SFRP1-mediated WNT/beta-catenin pathway in kainic acid-induced epilepsy

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (2)

Temporal lobe epilepsy (TLE) is a chronic disease of the nervous system, associated with increased proliferation in the hippocampus. Urothcarcinoma as......

Aberrant activation of Wnt/catenin signaling and overexpression of ABCG2 contributes to apoptosis down regulation and tumor progression of high grade ovarian cancer

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (1)

Side Population (SP) cells are the small pool of CSC like progenitor cells, which are drug resistant and recapitulate tumor generation. The occurrence......

Involvement of GPR30 in protection effect of Dexmedetomidine against myocardial ischemia/reperfusion injury in rat via AKT pathway

期刊: ACTA BIOCHIMICA POLONICA, 2021; 68 (1)

Acute myocardial infarction (AMI) is a heart disease that seriously threatens human health. Dexmedetomidine (DEX) has a certain protective effect on c......

共160条页码: 1/11页15条/页