期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ; ()
A novel acute viral pneumonia induced by SARS-CoV-2 exploded at the end of 2019, causing a severe medical and economic crisis. For developing specific......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ; ()
The epidermal growth factor receptor (EGFR) kinase inhibitors Gefitinib, Erlotinib, Afatinib and Osimertinib have been approved for the treatments of ......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ; ()
The emergence of COVID-19 took the world by shock in December 2019, starting from Wuhan, China and swiftly spreading across the globe. The number of C......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ; ()
The interaction properties of monensin/clopidol with bovine/human serum albumin (BSA/HSA) were determined via multispectral together with molecular mo......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ; ()
The binding interactions of bioactive compounds with proteins are of great importance in the food, biochemistry and pharmaceutical fields. Herein, the......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ; ()
Hydroxylated polychlorinated biphenyls (HO-PCBs), as the major metabolites of PCBs, have been reported to act as estrogen receptor beta (ER beta) agon......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ; ()
It has become obvious that fluorinated drugs have a significant role in medicinal applications. In this study, the fluorination of mirtazapine antidep......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ; ()
The antibacterial and antifungal effects of non-functionalized and surface-functionalized Mn3O4 nanoparticles were comparatively analyzed to reason ou......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ; ()
The FGF/FGFR system may affect tumor cells and stromal microenvironment through autocrine and paracrine stimulation, thereby significantly promoting o......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020; 38 (7)
Minidumbbell (MDB) is a newly found non-B DNA structure formed by short single-strand sequences. Up to now, three MDBs have been reported to form at n......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020; 38 (8)
Previous work has shown that edaravone inhibits fibrillogenesis of amyloid-beta protein (A beta). However, the detailed mechanism by which edaravone i......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020; 38 (8)
Receptor tyrosine kinase-like orphan receptor 1 (ROR1) has been recently proposed as a potential target for cancer treatment. It was suggested that mo......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020; 38 (9)
As an effective target in abnormal angiogenesis-related tumor treatment, VEGFR-2 has small-molecule inhibitors of various scaffolds being approved for......
期刊: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020; 38 (14)
The therapeutic potential of PPARs antagonists extends beyond diabetes. PPARs antagonists represent a new drug class that holds promise as a broadly a......