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Docosahexaenoic Acid Reverses Epithelial-Mesenchymal Transition and Drug Resistance by Impairing the PI3K/AKT/Nrf2/GPX4 Signalling Pathway in Docetaxel-Resistant PC3 Prostate Cancer Cells

期刊: FOLIA BIOLOGICA, 2022; 68 (2)

Drug resistance is a serious problem in cancer therapy. Growing evidence has shown that docosahexaenoic acid has anti-inflammatory and chemopreventive......

JIF:0.514

TRPM7 Elicits Proliferation and Differentiation of Human Lens Epithelial Cells through the TGF-beta/Smad Pathways

期刊: FOLIA BIOLOGICA, 2022; 68 (2)

Epithelial-mesenchymal transition (EMT) plays a crucial role in the development of cataract. This study aimed to explore the effects of TRPM7 on the p......

JIF:0.514

PLAG1 Promotes High Glucose-Induced Angiogenesis and Migration of Retinal Endothelial Cells by Regulating the Wnt/beta-Catenin Signalling Pathway

期刊: FOLIA BIOLOGICA, 2022; 68 (1)

Proliferation and migration of retinal en-dothelial cells (RECs) contribute to the development of diabetic retinopathy. PLAG1 (pleomorphic ade-noma ge......

JIF:0.514

Dynamic Molecular Profiles of Bone Marrow-Derived Osteoblasts at the Single-Cell Level

期刊: FOLIA BIOLOGICA, 2022; 68 (3)

Osteogenesis is an important process of bone metabolism, and abnormal osteogenesis leads to various skeletal system diseases. Osteoblasts, the main ce......

JIF:0.514

C-Phycocyanin Suppresses Cell Proliferation and Promotes Apoptosis by Regulating the AMPK Pathway in NCL-H292 Non-Small Cell Lung Cancer Cells

期刊: FOLIA BIOLOGICA, 2022; 68 (1)

Non-small cell lung cancer (NSCLC) re-sults in high mortality and has gained increasing at-tention. C-Phycocyanin (C-PC) has been identified as a pote......

JIF:0.514

RTKN2 Enhances Radioresistance in Gastric Cancer through Regulating the Wnt/beta-Catenin Signalling Pathway

期刊: FOLIA BIOLOGICA, 2022; 68 (1)

Adjuvant therapy and radiotherapy improves the survival of patients with metastatic and locally advanced gastric cancer (GC). However, the resistance ......

JIF:0.514

MicroRNA-214-3p Ameliorates LPS-Induced Cardiomyocyte Injury by Inhibiting Cathepsin B

期刊: FOLIA BIOLOGICA, 2022; 68 (2)

Myocardial injury is a common complica-tion of sepsis. MicroRNA (miRNA) miR-214-3p is protective against myocardial injury caused by sep-sis, but its ......

JIF:0.514

NFKB1 Signalling Activation Contributes to TRPV1 Over-expression via Repressing MiR-375 and MiR-455: a Study on Neuropathic Low Back Pain

期刊: FOLIA BIOLOGICA, 2022; 68 (3)

Transient receptor potential cation chan-nel subfamily V member 1 (TRPV1) has been found over-expressed in low back pain (LBP) patients with neuropath......

JIF:0.514

Investigation of the Inhibitory Effect of Platycodin D in Human Transitional Cell Carcinoma Cell Line 5637

期刊: FOLIA BIOLOGICA, 2021; 67 (1)

Platycodin D is an active component isolated from Chinese herb Platycodonis radix with various pharmacological activities, such as antitussive, expect......

Serum Cytokine Analysis Reveals Predictors of Progression from Chronic Hepatitis B to Liver Cirrhosis

期刊: FOLIA BIOLOGICA, 2021; 67 (1)

Hepatitis B virus (HBV) infection is more likely to develop into chronic and persistent infection in China, which is the main cause of chronic liver d......

Both Caspase and Calpain are Involved in Endoplasmic Reticulum-Targeted BNIP3-Induced Cell Death

期刊: FOLIA BIOLOGICA, 2020; 66 (2)

Bcl-2/E1B-19K-interacting protein 3 (BNIP3) is a member of the apoptotic B-cell lymphoma-2 family that regulates cell death. Although BNIP3 targeted n......

Deletions of the Idh1, Eco1, Rom2, and Taf10 Genes Differently Control the Hyphal Growth, Drug Tolerance, and Virulence of Candida albicans

期刊: FOLIA BIOLOGICA, 2020; 66 (3)

The most recent genome-editing system called CRISPR-Cas9 (clustered regularly interspaced short palindromic repeat system with associated protein 9-nu......

Indoleamine 2,3-Dioxygenase (IDO) Regulates Th17/Treg Immunity in Experimental IgA Nephropathy

期刊: FOLIA BIOLOGICA, 2019; 65 (2)

IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide. Current studies have shown that the Th17/Treg immune balance may be involved i......

JIF:1.07

PARP-1 Involvement in Autophagy and Their Roles in Apoptosis of Vascular Smooth Muscle Cells under Oxidative Stress

期刊: FOLIA BIOLOGICA, 2018; 64 (3)

Autophagy and poly(ADP-ribose) polymerase 1 (PARP-1) are activated and involved in a series of cell processes under oxidative stress, which is associa......

JIF:1.07

Oridonin Induces Apoptosis in Human Nasopharyngeal Carcinoma Cells Involving ROS Generation

期刊: FOLIA BIOLOGICA, 2017; 63 (4)

Oridonin, an ent-kaurene diterpenoid isolated from the traditional Chinese herb Rabdosia rubescens, has been reported to be a potent cytotoxic agent a......

JIF:1.04

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