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A Machine Learning Tool Using Digital Microscopy (Morphogo) for the Identification of Abnormal Lymphocytes in the Bone Marrow

期刊: ACTA CYTOLOGICA, 2021; 65 (4)

Morphological analysis of the bone marrow is an essential step in the diagnosis of hematological disease. The conventional analysis of bone marrow sme......

Developing a Machine Learning Algorithm for Identifying Abnormal Urothelial Cells: A Feasibility Study

期刊: ACTA CYTOLOGICA, 2021; 65 (4)

Introduction: Urine cytology plays an important role in diagnosing urothelial carcinoma (UC). However, urine cytology interpretation is subjective and......

Applying Probe Electrospray Ionization Mass Spectrometry to Cytological Diagnosis: A Preliminary Study by Using Cultured Lung Cancer Cells

期刊: ACTA CYTOLOGICA, 2021; 65 (5)

Objectives: Cytology and histology are 2 indispensable diagnostic tools for cancer diagnosis, which are rapidly increasing in importance with aging po......

The Application of DNA Ploidy Analysis in Large-Scale Population Screening for Cervical Cancer

期刊: ACTA CYTOLOGICA, 2021; 65 (5)

Objective: The objective of this study was to evaluate the application of DNA ploidy analysis in large-scale population screening for cervical cancer.......

The Value of Ultrasound-Guided Fine-Needle Aspiration Cytology Combined with Puncture Feeling in the Diagnosis of Thyroid Nodules

期刊: ACTA CYTOLOGICA, 2021; 65 (5)

Introduction: There are few studies on the role of puncture feeling in thyroid nodules during ultrasound-guided fine-needle aspiration cytology (US-FN......

Multigene Combined Detection by RT-qPCR Using Cytological Specimens

期刊: ACTA CYTOLOGICA, 2021; 65 (5)

Objective: The aim of the study was to investigate the mutation status of multiple driver genes by RT-qPCR and their significance in advanced lung ade......

The Application of Fine Needle Aspiration Biopsy in the Diagnosis of Axillary Masses

期刊: ACTA CYTOLOGICA, ; ()

Introduction: We intend to determine the diagnostic power of fine needle aspiration biopsy (FNAB) for differentiation between malignant and benign les......

Using Disposable Membrane Cell Collector to Enrich Lung Adenocarcinoma Cells in Bloody Pleural Effusion for Anaplastic Lymphoma Kinase Fusion Gene Detection

期刊: ACTA CYTOLOGICA, ; ()

Purpose: For anaplastic lymphoma kinase (ALK) gene detection, the centrifugal sedimentation method (CSM) and cell block method (CBM) are commonly used......

Axillary Nodal Metastasis with Papillary Morphology: An Uncommon Origin

期刊: ACTA CYTOLOGICA, 2020; 64 (6)

Background: Metastases to axillary lymph nodes are commonly and readily confirmed by fine needle aspiration cytology (FNAC). Most likely, these arise ......

Morphogo: An Automatic Bone Marrow Cell Classification System on Digital Images Analyzed by Artificial Intelligence

期刊: ACTA CYTOLOGICA, 2020; 64 (6)

Introduction: The nucleated-cell differential count on the bone marrow aspirate smears is required for the clinical diagnosis of hematological maligna......

Intracytoplasmic Lumen in Urine Cytology Predicts Worse Prognosis in Non-Muscle-Invasive Bladder Cancers

期刊: ACTA CYTOLOGICA, 2020; 64 (4)

Background:Intracytoplasmic lumina (ICL) are observed in several cancers, including urothelial carcinoma (UC). We have reported that ICL in urine cyto......

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