Neurovascular dysfunction is a primary or secondary cause in the pathogenesis of several cerebrovascular and neurodegenerative disorders, including st......
期刊: BRAIN PATHOLOGY, 2021; 31 (2)
Focal cortical dysplasia type IIb (FCDIIb) and tuberous sclerosis complex (TSC) are typical causes of developmental delay and refractory epilepsy. G-p......
期刊: BRAIN PATHOLOGY, 2021; 31 (2)
Polymorphisms in TMEM106B, a gene on chromosome 7p21.3 involved in lysosomal trafficking, correlates to worse neuropathological, and clinical outcomes......
期刊: BRAIN PATHOLOGY, 2020; 30 (1)
Some mouse models of Down syndrome (DS), including Ts1Cje mice, exhibit impaired prenatal neurogenesis with yet unknown molecular mechanism. To gain i......
期刊: BRAIN PATHOLOGY, 2020; 30 (1)
The "two-hit vascular hypothesis for Alzheimer's disease (AD)" and amyloid-beta (A beta) oligomer hypothesis suggest that impaired soluble A beta olig......
期刊: BRAIN PATHOLOGY, 2020; 30 (4)
cIMPACT-NOW (the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy) was established to evaluate and make practical recomme......
期刊: BRAIN PATHOLOGY, 2020; 30 (6)
Olfactory dysfunction is one of the early symptoms seen in Parkinson's disease (PD). However, the mechanisms underlying olfactory pathology that impac......
期刊: BRAIN PATHOLOGY, 2019; 29 (6)
Giant cell glioblastoma (gcGBM) is a rare histological variant of GBM, accounting for about 1% of all GBM. The prognosis is poor generally though gcGB......
Neuroinflammation is thought to play a pivotal role in the pathogenesis of periventricular white matter (PWM) damage (PWMD) induced by neonatal sepsis......