期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background Assessment of immune function is of key importance in recognition of disease or healthy status, which still faces challenge in clinical pra......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background Statins have been widely used to prevent cardiovascular disease in middle-aged and elderly populations; however, the effect of long-term tr......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background Grass carp are an important farmed fish in China that are infected by many pathogens, especially grass carp reovirus (GCRV). Notably, grass......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background: It has been widely accepted that monocytes are one of the central mediators contributing to inflammaging. However, it remains unclear whet......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Purpose This study aimed to explore the role of long non-coding RNA (lncRNA) BDNF-AS in the progression of multiple myeloma (MM). Methods The expressi......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background COVID-19 patients may experience cytokine storm when human immune system produces excessive cytokines/chemokines. However, it remains uncle......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Immunosenescence is the deterioration of the innate and adaptive immune systems associated with aging and is primarily characterized by a reduction in......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background Patients with systemic lupus erythematosus (SLE) are highly susceptible to infection and cardiovascular events, suggesting that chronic ant......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background Vaccination is important in influenza prevention but the immune response wanes with age. The circadian nature of the immune system suggests......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Microglia are immune-competent cells that are critically involved in maintaining normal brain function. A prominent characteristic of Alzheimer diseas......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and systemic immune-inflammation index (SII) are readily avail......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background The immune cell compartment of the mammalian brain changes dramatically and peripheral T cells infiltrate the brain parenchyma during norma......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background Systemic inflammation has been linked to diseases and frailty. However, little is known about the effect of systemic inflammation on frailt......
期刊: IMMUNITY & AGEING, 2022; 19 (1)
Background Depression is considered to be an immune-related disease; however, previous studies have focused on inflammatory factors, and there is no c......
期刊: IMMUNITY & AGEING, 2021; 18 (1)
The number of central and peripheral B cells and their responsiveness are decreased in aged mice. The diversity of mice central and peripheral B cell ......