期刊： CURRENT GENE THERAPY, 2022; 22 (5)
Background: Wet age-related macular degeneration (wAMD) is characterized by the presence of choroidal neovascularization (CNV). Although there are som......
期刊： CURRENT GENE THERAPY, 2022; 22 (5)
Background: Lung cancer is cancer with the highest incidence in the world, and there is obvious heterogeneity within its tumor. The emergence of singl......
期刊： CURRENT GENE THERAPY, 2022; 22 (5)
Background: Heterogeneous nuclear ribonucleoproteins (hnRNPs), a large family of RNA-binding proteins, have been implicated in tumor progression in mu......
期刊： CURRENT GENE THERAPY, 2022; 22 (1)
Lung adenocarcinoma (LUAD) is the common histological subtype of non-small-cell lung carcinoma (NSCLC). Circular RNAs (circRNAs) represent a new class......
期刊： CURRENT GENE THERAPY, 2022; 22 (1)
Background: Radiation-induced lung injury (RILI) is lacking effective therapeutic strategies. In this study, we conducted TGF-beta 1-based CRISPR/Cas9......
期刊： CURRENT GENE THERAPY, 2022; 22 (2)
Background: Increasing research reveals that long non-coding RNAs (lncRNAs) play an important role in various biological processes of human diseases. ......
期刊： CURRENT GENE THERAPY, 2022; 22 (4)
Background: Exosomes released from cardiomyocytes (CMs) potentially play an important role in angiogenesis through microRNA (miR) delivery. Studies ha......
期刊： CURRENT GENE THERAPY, 2022; 22 (4)
Background: Female fertility refers to the capacity to produce oocytes and achieve fertilization and pregnancy, and it is impaired by age, disease, en......
期刊： CURRENT GENE THERAPY, 2022; 22 (5)
Background: Signal transducer and activator of transcription 3 (STAT3) is an oncogene and frequently overexpressed in cancers. However, the regulatory......
期刊： CURRENT GENE THERAPY, 2022; 22 (1)
Aims: We aim to define parameters that affect the safety and long-term transgene expression of attenuated HSV-1 vectors and optimize the expression ca......
期刊： CURRENT GENE THERAPY, 2022; 22 (3)
Long non-coding RNAs (LncRNAs) are a type of RNA with little or no protein-coding ability. Their length is more than 200 nucleotides. A large number o......
期刊： CURRENT GENE THERAPY, 2022; 22 (3)
Background: The epidemic of SARS-CoV-2 has made COVID-19 a serious threat to human health around the world. The severe infections of SARS-CoV-2 are us......
期刊： CURRENT GENE THERAPY, 2022; 22 (4)
Bone Marrow Mesenchymal Stem Cells (BMSCs), multidirectional cells with self-renewal capacity, can differentiate into many cell types and play essenti......
期刊： CURRENT GENE THERAPY, 2022; 22 (4)
Background: GM1 gangliosidosis (GM1) is an autosomal recessive disorder characterized by the deficiency of beta-galactosidase (beta-gal), a ubiquitous......
期刊： CURRENT GENE THERAPY, 2022; 22 (1)
Hepatocellular carcinoma (HCC) is the sixth globally diagnosed cancer with a poor prognosis. Although the pathological factors of hepatocellular carci......
