A Novel DNA Aptamer Targeting S100P Induces Antitumor Effects in Colorectal Cancer Cells

期刊： NUCLEIC ACID THERAPEUTICS, 2020; 30 (6)

Colorectal cancer (CRC) is a prevalent malignancy with poor prognosis and survival. As a Ca(2+)binding protein, S100P plays a role in calcium-dependen......

Systemic Alanine Glyoxylate Aminotransferase mRNA Improves Glyoxylate Metabolism in a Mouse Model of Primary Hyperoxaluria Type 1

期刊： NUCLEIC ACID THERAPEUTICS, 2019; 29 (2)

Primary Hyperoxaluria Type 1 (PH1) is an autosomal recessive disorder of glyoxylate metabolism. Loss of alanine glyoxylate aminotransferase (AGT) func......

JIF：3.78

Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes

期刊： NUCLEIC ACID THERAPEUTICS, 2019; 29 (6)

The trinucleotide repeat containing 6 (TNRC6) family of proteins are core components of RNA interference (RNAi) and consist of three paralogs (TNRC6A,......

JIF：3.78

The BACE1-Specific DNA Aptamer A1 Rescues Amyloid-beta Pathology and Behavioral Deficits in a Mouse Model of Alzheimer's Disease

期刊： NUCLEIC ACID THERAPEUTICS, 2019; 29 (6)

Amyloid-beta (A beta) plaque deposits in the brain are considered to be one of the main pathological markers of Alzheimer's disease (AD). The sequenti......

JIF：3.78

An Integrative Multi-Omics Analysis Reveals MicroRNA-143 as Potential Therapeutics to Attenuate Retinal Angiogenesis

期刊： NUCLEIC ACID THERAPEUTICS, 2022; 32 (4)

Retinal neovascularization is a severe complication of proliferative diabetic retinopathy (PDR). MicroRNAs (miRNAs) are master regulators of gene expr......

JIF：4.922

Antisense Oligonucleotides Targeting Raf-1 Block Japanese Encephalitis Virus In Vitro and In Vivo

期刊： NUCLEIC ACID THERAPEUTICS, 2017; 27 (2)

Japanese encephalitis virus (JEV) infections represent a major health concern in Southeast Asia since no effective treatments are available. Recently,......

JIF：2.62