期刊： BMC BIOINFORMATICS, 2021; 22 (1)
Background: Interactions of microbes and diseases are of great importance for biomedical research. However, large-scale of microbe-disease interaction......
期刊： BMC BIOINFORMATICS, 2021; 22 (1)
Background One of the major challenges in precision medicine is accurate prediction of individual patient's response to drugs. A great number of compu......
期刊： BMC BIOINFORMATICS, 2021; 22 (1)
Background Normalization of RNA-seq data aims at identifying biological expression differentiation between samples by removing the effects of unwanted......
期刊： BMC BIOINFORMATICS, 2021; 22 (1)
Background Essential proteins have great impacts on cell survival and development, and played important roles in disease analysis and new drug design.......
期刊： BMC BIOINFORMATICS, 2021; 22 (SUPPL 6)
Background Genomic reads from sequencing platforms contain random errors. Global correction algorithms have been developed, aiming to rectify all poss......
期刊： BMC BIOINFORMATICS, 2021; 22 (1)
Background Single-cell RNA sequencing (scRNA-seq) is the most widely used technique to obtain gene expression profiles from complex tissues. Cell subs......
期刊： BMC BIOINFORMATICS, 2021; 22 (SUPPL 10)
Background Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal carcinoma and patients at advanced stage showed poor survival r......
期刊： BMC BIOINFORMATICS, 2021; 22 (SUPPL 10)
Background: More and more evidence shows that circRNA plays an important role in various biological processes and human health. Therefore, inferring t......
期刊： BMC BIOINFORMATICS, 2021; 22 (1)
Background: RNA regulates a variety of biological functions by interacting with other molecules. The ligand often binds in the RNA pocket to trigger s......
期刊： BMC BIOINFORMATICS, 2021; 22 (1)
Background Technological and research advances have produced large volumes of biomedical data. When represented as a network (graph), these data becom......
期刊： BMC BIOINFORMATICS, 2021; 22 (SUPPL 3)
Background: In the development of science and technology, there are increasing evidences that there are some associations between lncRNAs and human di......
期刊： BMC BIOINFORMATICS, 2021; 22 (1)
Background In recent years, various sequencing techniques have been used to collect biomedical omics datasets. It is usually possible to obtain multip......
期刊： BMC BIOINFORMATICS, 2021; 22 (1)
Background Gene Set Analysis (GSA) is arguably the method of choice for the functional interpretation of omics results. The following paper explores t......
期刊： BMC BIOINFORMATICS, 2021; 22 (1)
BackgroundStudies have shown that RNA secondary structure, a planar structure formed by paired bases, plays diverse vital roles in fundamental life ac......
期刊： BMC BIOINFORMATICS, 2021; 22 (SUPPL 6)
Background Nucleosome plays an important role in the process of genome expression, DNA replication, DNA repair and transcription. Therefore, the resea......
