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Vascular Smooth Muscle Cells Mechanosensitive Regulators and Vascular Remodeling

期刊： JOURNAL OF VASCULAR RESEARCH, 2022; 59 (2)

Blood vessels are subjected to mechanical loads of pressure and flow, inducing smooth muscle circumferential and endothelial shear stresses. The perce......

JIF：1.646

Association between Arteriosclerosis and Uncontrolled Blood Pressure in Patients with Essential Hypertension: Cross-Sectional Observational Study Results of the BEST Study

期刊： JOURNAL OF VASCULAR RESEARCH, 2022; 59 (3)

Whether arteriosclerosis can influence the hypertension control remains incompletely understood. We hypothesized that higher arteriosclerosis may be a......

JIF：1.646

CIDEC: A Potential Factor in Diabetic Vascular Inflammation

期刊： JOURNAL OF VASCULAR RESEARCH, 2022; 59 (2)

Cell death-inducing DFF45-like effector C (CIDEC) is involved in diet-induced adipose inflammation. Whether CIDEC plays a role in diabetic vascular in......

JIF：1.646

Protective Effects of 1,25 Dihydroxyvitamin D-3 against High-Glucose-Induced Damage in Human Umbilical Vein Endothelial Cells Involve Activation of Nrf2 Antioxidant Signaling

期刊： JOURNAL OF VASCULAR RESEARCH, 2021; 58 (4)

Aim: To explore the protective effects and related mech-anisms of 1,25 dihydroxyvitamin D-3 (1,25(OH)(2)D-3) on en-dothelial dysfunction under hypergl......

MiR-22-3p Suppresses Vascular Remodeling and Oxidative Stress by Targeting CHD9 during the Development of Hypertension

期刊： JOURNAL OF VASCULAR RESEARCH, 2021; 58 (3)

Hypertension is considered a risk factor for a series of systematic diseases. Known factors including genetic predisposition, age, and diet habits are......

Acute Hemodynamic Improvement by Thermal Vasodilation inside the Abdominal and Iliac Arterial Segments of Young Sedentary Individuals

期刊： JOURNAL OF VASCULAR RESEARCH, 2021; 58 (3)

Objective: To study the hemodynamic response to lower leg heating intervention (LLHI) inside the abdominal and iliac arterial segments (AIAS) of young......

Metformin Inhibits Abdominal Aortic Aneurysm Formation through the Activation of the AMPK/mTOR Signaling Pathway

期刊： JOURNAL OF VASCULAR RESEARCH, ; ()

Background and Objective: Epidemiological evidence suggests that the antidiabetic drug metformin (MET) can also inhibit abdominal aortic aneurysm (AAA......

Reciprocal Antagonism between MicroRNA-138 and SIRT1 and Its Implications for the Angiogenesis of Endothelial Cells

期刊： JOURNAL OF VASCULAR RESEARCH, 2021; 58 (2)

MicroRNAs and sirtuins are important epigenetic regulators of gene expression and both contribute significantly to postnatal vascular development. How......

Endothelium-Specific GTP Cyclohydrolase I Overexpression Restores Endothelial Function in Aged Mice

期刊： JOURNAL OF VASCULAR RESEARCH, 2021; 58 (2)

This study tested the hypothesis that endothelium-specific GTP cyclohydrolase I (GTPCH I) overexpression (Tg-GCH) restores age-associated endothelial ......

TMEM16A Regulates Pulmonary Arterial Smooth Muscle Cells Proliferation via p38MAPK/ERK Pathway in High Pulmonary Blood Flow-Induced Pulmonary Arterial Hypertension

期刊： JOURNAL OF VASCULAR RESEARCH, 2021; 58 (1)

Objective: Pulmonary arterial hypertension (PAH) is a complex disease of the small pulmonary arteries that is mainly characterized by vascular remodel......

Transient Receptor Potential Melastatin 7 Promotes Vascular Adventitial Fibroblasts Phenotypic Transformation and Inflammatory Reaction Induced by Mechanical Stretching Stress via p38 MAPK/JNK Pathway

期刊： JOURNAL OF VASCULAR RESEARCH, 2021; 58 (2)

Remodeling of the arteries is one of the pathological bases of hypertension. We have previously shown that transient receptor potential melastatin 7 (......

Direct Current Electric Field Stimulates Nitric Oxide Production and Promotes NO-Dependent Angiogenesis: Involvement of the PI3K/Akt Signaling Pathway

期刊： JOURNAL OF VASCULAR RESEARCH, 2020; 57 (4)

Electric fields (EFs) promote angiogenesis in vitro and in vivo. These results indicate the feasibility of the application of EFs to modulate angiogen......

Effect and Molecular Mechanisms of Collateral Vessel Growth Mediated by Activation of Transient Receptor Potential Vanilloid Type 1

期刊： JOURNAL OF VASCULAR RESEARCH, 2020; 57 (4)

Information on the function of transient receptor potential vanilloid 1 (TRPV1) in arteriogenesis is limited. We aimed to verify whether TRPV1 is invo......

Circulatory CD4-Positive T-Lymphocyte Imbalance Mediated by Homocysteine-Induced AIM2 and NLRP1 Inflammasome Upregulation and Activation Is Associated with Human Abdominal Aortic Aneurysm

期刊： JOURNAL OF VASCULAR RESEARCH, 2020; 57 (5)

Introduction:CD4-positive T lymphocytes (CD4 cells) play a significant role in human abdominal aortic aneurysm (AAA). However, we know little about th......

The Release of Cyclophilin A from Rapamycin-Stimulated Vascular Smooth Muscle Cells Mediated by Myosin II Activation: Involvement of Apoptosis but Not Autophagy

期刊： JOURNAL OF VASCULAR RESEARCH, 2020; 57 (5)

Introduction:The exocytosis of cyclophilin A (CyPA) by a vesicular pathway in response to reactive oxygen species has been determined. However, other ......

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