期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
Hepatocellular carcinoma is one of the most prevalent malignancies and a leading cause of cancer-related mortality worldwide. However, the therapies t......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
The present study aimed to investigate the in vivo inhibitory effect of histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) combined ......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
Traditional Chinese Herbal Medicine has been used to prevent and cure disease in China for thousands of years and has gained global interest in recent......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
A series of 2,3-dioxoindolin-N-phenylacetamide derivatives was evaluated for inhibitory activity against CDC25B and PTP1B enzymes. Most of the derivat......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
p21-activated kinase 6 (PAK6) is a member of the PAK family of serine/threonine kinases that are known effectors of Rho GTPases Cdc42 and Rac. PAKs re......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
In the present study, a series of novel 5,7-diisoprenyloxyflavone derivatives were designed, synthesized, and evaluated for their antibacterial activi......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
Diacerein is a symptomatic slow-acting drug used for treating osteoarthritis. This drug is completely metabolized into the active metabolite rhein bef......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
Currently, the use of natural compounds obtained from plants tremendously increased due to their promising therapeutic properties. The aim of this stu......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
Given their relationship with metabolic syndrome and systematic inflammatory diseases, the pathogenesis of hypertension, hyperglycemia, and hyperlipid......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
The 4-Hydroxycoumarin derivatives are known to show a broad spectrum of pharmacological applications. In this paper we are reporting the synthesis of ......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
To assess the effect of nesiritide on the endothelial function of iliac arteries following endothelia trauma. Right iliac artery trauma was created wi......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020; 56 ()
T lymphocytes, cytokines, and macrophages play important roles in the clearance of Mycobacterium tuberculosis (Mtb) by the immune system. This study a......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019; 55 ()
Rhubarb is commonly used as a cathartic in Asian countries. However, researchers have devotedextensive concerns to the quality control and safety of r......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019; 55 ()
To study the effect of small interfering RNA targeting metastasis-associated lung adenocarcinoma transcript) (si-MALAT1) combining with curcumin on th......
期刊: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019; 55 ()
The present study aimed to investigate the protective effects of salidroside on chronic heart failure (CHF) in rats and to explore the underlying mech......