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Restoration of NAD(+) homeostmis protects C2C12 myoblasts and mouse levator ani muscle from mechanical stress-induced damage

期刊: ANIMAL CELLS AND SYSTEMS, 2022; 26 (4)

Excessive mechanical traction damages the levator ani muscle (LAM), increasing the incidence of pelvic floor dysfunction (PFD). In this study, we expl......

JIF:1.704

Beneficial effect of simvastatin on human umbilical vein endothelial cells gap junctions induced by TNF-alpha

期刊: ANIMAL CELLS AND SYSTEMS, 2022; 26 (1)

Although simvastatin has been shown to inhibit vascular permeability, which might be amplified via gap junction intercellular communication (GJIC), th......

JIF:1.704

Comprehensive analysis of the prognostic value and immune implications of the TTK gene in lung adenocarcinoma: a meta-analysis and bioinformatics analysis

期刊: ANIMAL CELLS AND SYSTEMS, 2022; 26 (3)

Background High expression levels of the TTK gene are closely related to tumor occurrence and poor prognosis, as confirmed by some studies. Our study ......

JIF:1.704

Analyzing and validating the prognostic value and immune microenvironment of clear cell renal cell carcinoma

期刊: ANIMAL CELLS AND SYSTEMS, 2022; 26 (2)

Tumor immune microenvironment (TIME) plays an important role in tumor diagnosis, prevention, treatment and prognosis. However, the correlation and pot......

JIF:1.704

CXCL12 secreted by pancreatic stellate cells accelerates gemcitabine resistance of pancreatic cancer by enhancing glycolytic reprogramming

期刊: ANIMAL CELLS AND SYSTEMS, 2022; 26 (4)

Pancreatic stellate cells (PSCs) are the primary cell components of pancreatic cancer (PC) and are involved in tumor growth, metastasis and resistance......

JIF:1.704

CKS1B promotes the progression of hepatocellular carcinoma by activating JAK/STAT3 signal pathway

期刊: ANIMAL CELLS AND SYSTEMS, 2021; 25 (4)

Hepatocellular carcinoma (HCC) is a malignancy of considerable concern due to its continuous increase in morbidity and mortality. This study attempts ......

Type II transmembrane serine proteases 4 (TMPRSS4) promotes proliferation, invasion and epithelial-mesenchymal transition in endometrial carcinoma cells (HEC1A and Ishikawa) via activation of MAPK and AKT

期刊: ANIMAL CELLS AND SYSTEMS, 2021; 25 (4)

Endometrial cancer is the most common gynecological cancer in the developed countries. Type II transmembrane serine proteases 4 (TMPRSS4) is a newly d......

MCT2 overexpression promotes recovery of cognitive function by increasing mitochondrial biogenesis in a rat model of stroke

期刊: ANIMAL CELLS AND SYSTEMS, 2021; 25 (2)

Monocarboxylate transporter 2 (MCT2) is the predominant monocarboxylate transporter expressed by neurons. MCT2 plays an important role in brain energy......

Desmoglein 3 contributes to tumorigenicity of pancreatic ductal adenocarcinoma through activating Src-FAK signaling

期刊: ANIMAL CELLS AND SYSTEMS, 2021; 25 (3)

Desmogleins (DSGs), with the ability to link adjacent cells, have been shown to participate in the development of malignancy. DSG3 was up-regulated in......

MTBP promoted the proliferation, migration and invasion of colon cancer cells by activating the expression of ZEB2

期刊: ANIMAL CELLS AND SYSTEMS, 2021; 25 (3)

Colon cancer is a malignant tumor that seriously affects human health. Recently, studies revealed that the expression of MTBP enhanced the proliferati......

Aquaporin-1 facilitates proliferation and invasion of gastric cancer cells via GRB7-mediated ERK and Ras activation

期刊: ANIMAL CELLS AND SYSTEMS, 2020; 24 (5)

Gastric cancer, one of the most common malignant tumors of the digestive tract, is devoid of effective treatment owing to its highly invasive ability.......

JAK2-STAT5 signaling is insensitive to porcine growth hormone (pGH) in hepatocytes of neonatal pig

期刊: ANIMAL CELLS AND SYSTEMS, 2020; 24 (2)

Porcine growth hormone (pGH) is most important hormone which is involved in the growth and development of pig. However, a series of studies have indic......

Knockdown of LncRNAZFAS1 suppresses cell proliferation and metastasis in non-small cell lung cancer

期刊: ANIMAL CELLS AND SYSTEMS, 2020; 24 (2)

To evaluate the effects of LncRNAZFAS1 on cell proliferation and tumor metastasis in non-small cell lung cancer (NSCLC), we detected the expression le......

Identification and prevention of heterotopias in mouse neocortical neural cell migration incurred by surgical damages during utero electroporation procedures

期刊: ANIMAL CELLS AND SYSTEMS, 2020; 24 (2)

In utero electroporation (IUE) is a useful technique for gene delivery in embryonic mouse brain. IUE technique is used to investigate the mammalian br......

miR-424-5p regulates apoptosis and cell proliferation via targeting Bcl2 in nucleus pulposus cells

期刊: ANIMAL CELLS AND SYSTEMS, 2020; 24 (3)

Background miRNAs play an important role in the pathogenesis of intervertebral disc degeneration (IDD). The role and the underlying mechanism of miR-4......

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