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The influence of TCM constitutions and neurocognitive function in elderly Macau individuals

期刊: CHINESE MEDICINE, 2021; 16 (1)

Background: Traditional Chinese medicine (TCM) constitution contributes to predicating disease occurrence and pathological progress. In this study, we......

Integrating metabolomic data with machine learning approach for discovery of Q-markers from Jinqi Jiangtang preparation against type 2 diabetes

期刊: CHINESE MEDICINE, 2021; 16 (1)

Background Jinqi Jiangtang (JQJT) has been widely used in clinical practice to prevent and treat type 2 diabetes. However, little research has been do......

Soufeng sanjie formula alleviates collagen-induced arthritis in mice by inhibiting Th17 cell differentiation

期刊: CHINESE MEDICINE, 2021; 16 (1)

Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease. Soufeng sanjie formula (SF), which is composed of scolopendra (dried body of Sc......

Shenzhi Jiannao formula ameliorates vascular dementia in vivo and in vitro by inhibition glutamate neurotoxicity via promoting clathrin-mediated endocytosis

期刊: CHINESE MEDICINE, 2021; 16 (1)

Background: Synaptic damage and glutamate excitotoxicity have been implicated in the pathogenesis of vascular dementia (VD). Clathrin, RAB5B and N-met......

Traditional Chinese Medicine in nonalcoholic fatty liver disease: molecular insights and therapeutic perspectives

期刊: CHINESE MEDICINE, 2021; 16 (1)

Nonalcoholic fatty liver disease (NAFLD) has become the world's largest chronic liver disease, while there is still no specific drug to treat NAFLD. T......

Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo

期刊: CHINESE MEDICINE, 2021; 16 (1)

Background: Polyphyllin VII (PP7), a steroidal saponin from P. polyphylla has been found to exert strong anticancer activity. Little is known about th......

Electroacupuncture reduces cold stress-induced pain through microglial inactivation and transient receptor potential V1 in mice

期刊: CHINESE MEDICINE, 2021; 16 (1)

Background The treatment, and efficacy thereof, is considered to be inadequate with specificity to alleviation of Fibromyalgia and its associated pain......

Transcriptomics-based analysis of the mechanism by which Wang-Bi capsule alleviates joint destruction in rats with collagen-induced arthritis

期刊: CHINESE MEDICINE, 2021; 16 (1)

Background Rheumatoid arthritis (RA) is a chronic autoimmune disease accompanied with joint destruction that often leads to disability. Wang-Bi capsul......

Zoology, chemical composition, pharmacology, quality control and future perspective of Musk (Moschus): a review

期刊: CHINESE MEDICINE, 2021; 16 (1)

Musk, the dried secretion from the musk sac gland which is located between the navel and genitals of mature male musk deer, is utilized as oriental me......

Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway

期刊: CHINESE MEDICINE, 2021; 16 (1)

Background: Tanshinone I (TI) is a primary component of Salvia miltiorrhiza Bunge (Danshen), which confers a favorable role in a variety of pharmacolo......

Herbal formula Huangqi Guizhi Wuwu decoction attenuates paclitaxel-related neurotoxicity via inhibition of inflammation and oxidative stress

期刊: CHINESE MEDICINE, 2021; 16 (1)

Background Paclitaxel-induced peripheral neuropathy (PIPN) is a challenging clinical problem during chemotherapy. Our previous work found that herbal ......

West meets east: open up a dialogue on phytomedicine

期刊: CHINESE MEDICINE, 2021; 16 (1)

The desire to extend the wisdom of traditional health systems has motivated the trade of many phytomedicine on a global scale for centuries, especiall......

The role of macrophage polarization and associated mechanisms in regulating the anti-inflammatory action of acupuncture: a literature review and perspectives

期刊: CHINESE MEDICINE, 2021; 16 (1)

Acupuncture is used in the treatment of a variety of inflammatory conditions and diseases. However, the mechanisms of its anti-inflammatory action are......

Assessment of the reporting quality of randomised controlled trials of massage

期刊: CHINESE MEDICINE, 2021; 16 (1)

Objective To assess the reporting quality of randomised controlled trials (RCTs) of massage, particularly whether necessary elements related to massag......

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