期刊： GENES & DISEASES, 2021; 8 (3)
Preeclampsia is a pregnancy complication which threatens the survival of mothers and fetuses. It originates from abnormal placentation, especially ins......
期刊： GENES & DISEASES, 2021; 8 (3)
Plasmid DNA (pDNA) isolation from bacterial cells is one of the most common and critical steps in molecular cloning and biomedical research. Almost al......
期刊： GENES & DISEASES, 2021; 8 (5)
According to existing reports, mutations in the slow tropomyosin gene (TPM3) may lead to congenital fiber-type disproportion (CFTD), nemaline myopathy......
期刊： GENES & DISEASES, 2021; 8 (5)
The Patched 1 (PTCH1) gene encodes a membrane receptor involved in the Hedgehog (Hh) signaling pathway, an abnormal state of which may result in conge......
期刊： GENES & DISEASES, 2021; 8 (5)
CTLA4 deficiency and LRBA deficiency are a group disorders of immune dysregulation that affect CTLA4 pathway. The patients mainly present with autoimm......
期刊： GENES & DISEASES, 2021; 8 (5)
Adipocytes and immune cells are vital for the development of adipose tissue. Adipokines secreted by adipocytes regulate adipogenesis and body metaboli......
期刊： GENES & DISEASES, 2021; 8 (5)
Insulin-resistance (IR) is one of the most important precursors of type 2 diabetes (T2D). Recent evidence suggests an association of depression with t......
期刊： GENES & DISEASES, 2021; 8 (4)
Hypertension (HT) is the most common public-health challenge and shows a high incidence around the world. Cardiovascular diseases are the leading caus......
期刊： GENES & DISEASES, 2021; 8 (4)
CircRNAs are a large class of endogenous single-stranded RNA that is different from other linear RNA, which are produced by back-splicing and fusion o......
期刊： GENES & DISEASES, 2021; 8 (4)
Diabetes is an age-related disease, most of which is type 2 diabetes, and islet beta cell dysfunction and insulin resistance are the main mechanisms o......
期刊： GENES & DISEASES, 2021; 8 (4)
As a potential chemo-therapeutic agent, all-trans retinoic acid (ATRA) can significantly reverse epithelial-me senchymal transition (EMT) of hepal-6 h......
期刊： GENES & DISEASES, 2021; 8 (5)
Secreted frizzled-related protein 5 (SFRP5) plays a pivotal role in regulating the development of many tissues and organs, however, as an inhibitor of......
期刊： GENES & DISEASES, 2021; 8 (3)
The presence of VPS33B in tumors has rarely been reported. Downregulated VPS33B protein expression is an unfavorable factor that promotes the pathogen......
期刊： GENES & DISEASES, 2021; 8 (5)
Mitochondrial autophagy (mitophagy) is the selective clearance of damaged or incomplete mitochondria by autophagy, which is critical for the functiona......
期刊： GENES & DISEASES, 2021; 8 (5)
PIWI-interacting RNA (piRNAs), once thought to be mainly functioning in germlines, are now known to play an essential role in somatic and cancerous ti......
