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Aquatic Viruses and Climate Change

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2021; 41 ()

The viral component in aquatic systems clearly needs to be incorporated into future ocean and inland water climate models. Viruses have the potential ......

Network Pharmacology and Molecular Docking Combined to Analyze the Molecular and Pharmacological Mechanism of Pinellia ternata in the Treatment of Hypertension

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2021; 43 (1)

Hypertension is a cardiovascular disease that causes great harm to health and life, affecting the function of important organs and accompanied by a va......

Three-Dimensional Reconstructed Bone Marrow Matrix Culture Improves the Viability of Primary Myeloma Cells In-Vitro via a STAT3-Dependent Mechanism

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2021; 43 (1)

Primary myeloma (PM) cells are short-lived in conventional culture, which limited their usefulness as a study model. Here, we evaluated if three-dimen......

Stealth Strategies of Mycobacterium tuberculosis for Immune Evasion

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2021; 41 ()

Tuberculosis is a devastating disease causing high mortality all over the world, especially in the developing countries. Mycobacterium tuberculosis (M......

Pancreatic Islets Exhibit Dysregulated Adaptation of Insulin Secretion after Chronic Epinephrine Exposure

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2021; 43 (1)

Chronic adrenergic stimulation is the dominant factor in impairment of the beta-cell function. Sustained adrenergic exposure generates dysregulated in......

OASs in Defense of Mycobacterial Infection: Angels or Demons?

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2021; 40 ()

The interaction between pattern-recognition receptors (PRRs) and pathogen-associated molecular patterns (PAMPs) induces type I interferon (IFN) respon......

Progress in the Discovery of Small Molecule Modulators of DeSUMOylation

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2020; 35 ()

SUMOylation and DeSUMOylation are reversible protein post-translational modification (PTM) processes involving small ubiquitin-like modifier ( SUMO) p......

Earth's Stratosphere and Microbial Life

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2020; 38 ()

The Earth's atmosphere is an extremely large and sparse environment which is quite challenging for the survival of microorganisms. We have long wonder......

Exploring Deep-Sea Brines as Potential Terrestrial Analogues of Oceans in the Icy Moons of the Outer Solar System

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2020; 38 ()

Several icy moons of the outer solar system have been receiving considerable attention and are currently seen as major targets for astrobiological res......

A Review on Salivary Proteomics for Oral Cancer Screening

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2020; 37 ()

Oral cancer has emerged as a global health problem due to its relatively high incidence and mortality. Human saliva as a diagnostic fluid can offer an......

OASs in Defense of Mycobacterial Infection: Angels or Demons?

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2020; 40 ()

The interaction between pattern-recognition receptors (PRRs) and pathogen-associated molecular patterns (PAMPs) induces type I interferon (IFN) respon......

Recent Advances in Pathogenic Streptococcus Vaccine Development

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2019; 32 ()

Streptococcus pneumoniae (Spn) and Streptococcus pyogenes (Spy) cause many invasive and noninvasive diseases responsible for high morbidity and mortal......

JIF:2.51

Progress of Antimicrobial Discovery Against the Major Cariogenic Pathogen Streptococcus mutans

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2019; 32 ()

Dental caries, also known as tooth decay, or cavities, remains a global public health issue. Streptococcus mutans is considered the most significant c......

JIF:2.51

Molecular Evolution of Clinical Pathogenic Streptococci

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2019; 32 ()

The genus Streptococcus comprises a wide variety of pathogenic and commensal gram-positive bacteria, many of which the pathogenic species cause severe......

JIF:2.51

The Adhesion and Invasion Mechanisms of Streptococci

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2019; 32 ()

Streptococci are common human pathogens, colonizing multiple parts of the human body such as the upper respiratory tract, urethra, gastrointestinal tr......

JIF:2.51

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