Study Objective Prophylactic norepinephrine infusion effectively lowers the incidence of postspinal anesthesia hypotension. The optimal prophylactic d......
期刊： PHARMACOTHERAPY, 2021; 41 (2)
Background Cirrhotic patients are at a high risk of fungal infections. Voriconazole is widely used as prophylaxis and in the treatment of invasive fun......
期刊： PHARMACOTHERAPY, 2021; 41 (3)
Objectives The objective of this study was to establish physiologically based pharmacokinetic (PBPK) models of tramadol and its active metabolite O-de......
期刊： PHARMACOTHERAPY, 2021; 41 (2)
Objective To evaluate the impact of pre-intensive care unit admission (pre-ICU) statin use on all-cause in-hospital mortality and ICU length of stay (......
期刊： PHARMACOTHERAPY, 2020; 40 (7)
Background It is known that gamma-glutamyl hydrolase (GGH) is involved in the disposition of methotrexate (MTX), and GGH activity is regulated by DNA ......
期刊： PHARMACOTHERAPY, 2020; 40 (7)
Objectives To evaluate the pharmacokinetic properties and safety of empagliflozin, and the bioequivalence of test formulation empagliflozin tablet com......
期刊： PHARMACOTHERAPY, 2020; 40 (10)
Background Opioid prescribing by dentists for older patients receiving medications with potential contraindications and the subsequent impact on acute......
期刊： PHARMACOTHERAPY, 2020; 40 (4)
Study Objective Lack of blood pressure control is often seen in hypertensive patients concomitantly taking antituberculosis medications due to the com......
期刊： PHARMACOTHERAPY, 2019; 39 (1)
Background There are limited markers that could facilitate individualized tacrolimus treatment in the early posttransplantation period. Genetic factor......
期刊： PHARMACOTHERAPY, 2019; 39 (12)
Study Objectives To compare the effectiveness of different taxane-containing regimens and to identify the best strategy for the treatment of human epi......
Background The pathogenic mechanism of antituberculous drug-induced liver injury (ATDILI) is associated with antioxidant enzymes. The objective of the......
期刊： PHARMACOTHERAPY, 2019; 39 (6)
Study Objective To compare the efficacy and safety of once-weekly and twice-weekly bortezomib therapy in patients with hematologic malignancies. Desig......
期刊： PHARMACOTHERAPY, 2019; 39 (10)
Objectives Few studies have investigated the prophylactic efficacy of dexmedetomidine (DEX) in postpartum depressive symptoms (PDS). A randomized doub......
期刊： PHARMACOTHERAPY, 2019; 39 (12)
Objective To identify the pharmacokinetic differences of antiretroviral drugs between HIV-infected Chinese patients and patients of other race/ethnici......
