筛选条件 共查询到259条结果
排序方式
Panax Notoginseng Saponins Promote Cell Death and Chemosensitivity in Pancreatic Cancer through the Apoptosis and Autophagy Pathways

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (13)

Background: Panax Notoginseng Saponins (PNS) is used as a traditional Chinese medicine for ischemic stroke and cardiovascular disease; it has been pro......

The Potential Clinical Value of Curcumin and its Derivatives in Colorectal Cancer

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (13)

Background: Curcumin, a naturally occurring polyphenol, possesses pleiotropic pharmacologic properties, including anti-inflammatory and anti-oxidant a......

Discovery and Design of Peptides as MMP9 Inhibitors through Structure-Based Molecular Docking for Targeted Mantle Cell Lymphoma Therapy

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (12)

Background: Enhanced expression and activation of metalloproteinase-9 (MMP9) are associated with mantle cell lymphoma (MCL) progression, invasion and ......

FOXM1-Dependent Transcriptional Regulation of EZH2 Induces Proliferation and Progression in Prostate Cancer

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (14)

Background: Prostate cancer is one of the most commonly diagnosed cancers and one of the most common causes of cancer-related deaths among men worldwi......

Resveratrol and other Stilbenes: Effects on Dysregulated Gene Expression in Cancers and Novel Delivery Systems

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (5)

Trans-resveratrol (RESV), pterostilbene, trans-piceid and trans-viniferins are bioactive stilbenes present in grapes and other plants. Several groups ......

Recent Progress in the Development of Quinoline Derivatives for the Exploitation of

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (7)

Background: Along with the progress in medicine and therapies, the exploitation of anti-cancer agents focused more on the vital signaling pathways and......

Anti-Tumor Activity and Underlying Mechanism of Phomoxanthone B in MCF7 Cells

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (14)

Background: Xanthones are a class of heterocyclic natural products, which are promising sources of anti-cancer leads. Phomoxanthone B (PXB) and Phomox......

Human Papillomavirus E7 Oncoprotein Promotes Proliferation and Migration through the Transcription Factor E2F1 in Cervical Cancer Cells

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (13)

Background: High-risk human papillomavirus (HR-HPV) persistent infection is the main cause of cervical cancer and its precancerous lesions. A previous......

Construction and Validation of Prognostic Markers of Liver Cancer Based on Autophagy Genes

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (14)

Background: Liver cancer is one of the most common diseases in the world. At present, the mechanism of autophagy genes in liver cancer is not very cle......

Development of Furo[2,3-b]quinoline Derivatives with Anti-Breast Cancer Property by Targeting Topoisomerase II

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (12)

A number of novel furo[2,3-b]quinoline derivatives were designed and synthesized by introducing different substituted anilines and phenols to C4-posit......

The Efficacy and Safety of Additional Anti-HER2-Targeting Drugs in the Treatment of HER2-Positive Advanced Breast Cancer: A Meta-Analysis

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (14)

Background: HER2-positive breast cancer patients account for one-fifth of the total breast cancer population. Besides, more anti-HER2-targeting drugs ......

Downregulation of GPR4 and TCF7 Promotes Apoptosis and Inhibits Growth and Invasion of Ovarian Cancer Cells

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (12)

Background: G protein-coupled receptor 4 (GPR4) has been reported to play essential roles in regulating the proliferation, migration and angiogenesis ......

Novel Scopoletin Derivatives Kill Cancer Cells by Inducing Mitochondrial Depolarization and Apoptosis

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (14)

Background: Natural products and their molecular frameworks have been explored as invaluable sources of inspiration for drug design by means of struct......

Linc01559 Served as a Potential Oncogene and Promoted Resistance of Hepatocellular Carcinoma to Oxaliplatin by Directly Sponging miR-6783-3p

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (2)

Background: Oxaliplatin (L-OHP)-based chemotherapy, such as FOLFOX4 (5-fluorouracil, leucovorin, and L-OHP), improves the prognosis of patients with l......

Periplogenin Activates ROS-ER Stress Pathway to Trigger Apoptosis via BIP-eIF2 alpha-CHOP and IRE1 alpha-ASK1-JNK Signaling Routes

期刊: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021; 21 (1)

Background: Periplogenin (PPG), a natural compound isolated from traditional Chinese herb Cortex Periplocae, has been reported to possess anti-inflamm......

共259条页码: 1/18页15条/页