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Promising Immunotherapies against COVID-19

期刊: ADVANCED THERAPEUTICS, 2021; 4 (8)

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a severe pandemic and deeply a......

Targeting Lymphoid Tissues to Promote Immune Tolerance

期刊: ADVANCED THERAPEUTICS, 2021; 4 (8)

The enormous research progress in autoimmune disorders makes the establishment of long-term clinical tolerance to autoantigens an accessible goal. Thi......

Ultrasound-Responsive Microfluidic Microbubbles for Combination Tumor Treatment

期刊: ADVANCED THERAPEUTICS, 2021; 4 (7)

Anticancer treatment is a worldwide challenge, and there are constant endeavors in this field to develop intelligent drug delivery systems to improve ......

Harnessing Artificial Intelligence to Expedite Identification of Therapeutic Phytochemical Combination for Alcoholic Hepatic Injury

期刊: ADVANCED THERAPEUTICS, 2021; 4 (6)

Plant-originated compounds, also known as phytochemicals, could improve health through either daily consumption or medical treatments. Conventional de......

Enhanced Targeting and Immune Activation of Tumor Microenvironment by Nanomodified Anti-PD1 in Liver Cancer

期刊: ADVANCED THERAPEUTICS, 2021; 4 (6)

Liver cancer is one of the most common cancers worldwide, 75% of which are hepatocellular carcinoma (HCC). Generally, chronic inflammation and an immu......

Inhaled Dry Powder Formulation of Tamibarotene, a Broad-Spectrum Antiviral against Respiratory Viruses Including SARS-CoV-2 and Influenza Virus

期刊: ADVANCED THERAPEUTICS, 2021; 4 (7)

In response to the epidemic and pandemic threats caused by emerging respiratory viral infections, a safe and efficient broad-spectrum antiviral therap......

Lipid Nature and Alkyl Length Influence Lymph Node Accumulation of Lipid-Polyethylene Glycol Amphiphiles

期刊: ADVANCED THERAPEUTICS, 2021; 4 (8)

Immunomodulatory drugs are of great relevance in the context of vaccine delivery and cancer immunotherapy. Due to the ubiquitous presence of immune ce......

Ultrasound-Triggered In Situ Gelation to Overcome Tumor Hypoxia for Enhanced Photodynamic and Sustained Chemotherapy

期刊: ADVANCED THERAPEUTICS, 2021; 4 (7)

The combination of photodynamic therapy (PDT) and chemotherapy (CT) has promising potential for cancer treatment in overcoming drug resistance and sub......

Progress and Prospects of Regulatory Functions Mediated by Nitric Oxide on Immunity and Immunotherapy

期刊: ADVANCED THERAPEUTICS, 2021; 4 (8)

Nitric oxide (NO), as a crucial signaling biomolecule, is closely involved in the cardiovascular, immune, and central nervous system. NO not only part......

Expansion of Rare Cancer Cells into Tumoroids for Therapeutic Regimen and Cancer Therapy

期刊: ADVANCED THERAPEUTICS, 2021; 4 (7)

Rare cancer cells, such as circulating tumor cells (CTCs) and cancer stem cells (CSCs), are small cell population found in cancer patients. CTCs have ......

Synergistic Photothermal and Chemical Therapy by Smart Dual-Functional Graphdiyne Nanosheets for Treatment of Parkinson's Disease

期刊: ADVANCED THERAPEUTICS, 2021; 4 (7)

Successful treatment of Parkinson's disease (PD) is impeded by limited permeability of the blood brain barrier (BBB) which causes unsatisfactory drug ......

Drug Repurposing for the Treatment of COVID-19: A Knowledge Graph Approach

期刊: ADVANCED THERAPEUTICS, 2021; 4 (7)

Identifying effective drug treatments for COVID-19 is essential to reduce morbidity and mortality. Although a number of existing drugs have been propo......

Targeting Signaling Pathways of Hyaluronic Acid and Integrin Receptors by Synergistic Combination Nanocomposites Inhibits Systemic Metastases and Primary Triple Negative Breast Cancer

期刊: ADVANCED THERAPEUTICS, 2021; 4 (6)

Triple negative breast cancer (TNBC) has a poor prognosis due to its aggressive nature, high incidence of distant metastasis, and lack of targets for ......

Fluorinated Chitosan Mediated Synthesis of Copper Selenide Nanoparticles with Enhanced Penetration for Second Near-Infrared Photothermal Therapy of Bladder Cancer

期刊: ADVANCED THERAPEUTICS, 2021; 4 (7)

The emergence of near-infrared-II (NIR-II) light activated photomedicines has extended the penetration depth for noninvasive theranostics, especially ......

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