筛选条件 共查询到25条结果
排序方式
Two neuroanatomical subtypes of males with autism spectrum disorder revealed using semi-supervised machine learning

期刊: MOLECULAR AUTISM, 2022; 13 (1)

Background Clinical and etiological varieties remain major obstacles to decompose heterogeneity in autism spectrum disorders (ASD). Recently, neuroima......

JIF:6.874

Autism-associated protein POGZ controls ESCs and ESC neural induction by association with esBAF

期刊: MOLECULAR AUTISM, 2022; 13 (1)

Background The POGZ gene has been found frequently mutated in neurodevelopmental disorders (NDDs), particularly autism spectrum disorder (ASD) and int......

JIF:6.874

Inter-individual heterogeneity of functional brain networks in children with autism spectrum disorder

期刊: MOLECULAR AUTISM, 2022; 13 (1)

Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with considerable clinical heterogeneity. This study aimed to explore the ......

JIF:6.874

Assessing the requirements of prenatal UBE3A expression for rescue of behavioral phenotypes in a mouse model for Angelman syndrome

期刊: MOLECULAR AUTISM, 2020; 11 (1)

Background Angelman syndrome (AS) is a rare neurodevelopmental disorder caused by the loss of functional ubiquitin protein ligase E3A (UBE3A). In neur......

Autistic traits, systemising, empathising, and theory of mind in transgender and non-binary adults

期刊: MOLECULAR AUTISM, 2020; 11 (1)

Background Prior research examining autistic traits in gender minority adults has reported mixed findings. Most prior studies did not include non-bina......

Differential mirror neuron system (MNS) activation during action observation with and without social-emotional components in autism: a meta-analysis of neuroimaging studies

期刊: MOLECULAR AUTISM, 2020; 11 (1)

Background Impaired imitation has been found to be an important factor contributing to social communication deficits in individuals with autism spectr......

Functional relationships between recessive inherited genes and genes with de novo variants in autism spectrum disorder

期刊: MOLECULAR AUTISM, 2020; 11 (1)

Background: Both de novo variants and recessive inherited variants were associated with autism spectrum disorder (ASD). This study aimed to use exome ......

Developmental vitamin D deficiency increases foetal exposure to testosterone

期刊: MOLECULAR AUTISM, 2020; 11 (1)

Background Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders which are more common in males. The 'prenatal sex steroid' hypoth......

Common and unique multimodal covarying patterns in autism spectrum disorder subtypes

期刊: MOLECULAR AUTISM, 2020; 11 (1)

Background The heterogeneity inherent in autism spectrum disorder (ASD) presents a substantial challenge to diagnosis and precision treatment. Heterog......

Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons

期刊: MOLECULAR AUTISM, 2020; 11 (1)

Background MBD5, encoding the methyl-CpG-binding domain 5 protein, has been proposed as a necessary and sufficient driver of the 2q23.1 microdeletion ......

The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior

期刊: MOLECULAR AUTISM, 2020; 11 (1)

Background The regulation of protein synthesis is a critical step in gene expression, and its dysfunction is implicated in autism spectrum disorder (A......

Transcriptomics of Gabra4 knockout mice reveals common NMDAR pathways underlying autism, memory, and epilepsy

期刊: MOLECULAR AUTISM, 2020; 11 (1)

Autism spectrum disorder (ASD) is a neuronal developmental disorder with impaired social interaction and communication, often with abnormal intelligen......

Dysregulation of protein synthesis and dendritic spine morphogenesis in ASD: studies in human pluripotent stem cells

期刊: MOLECULAR AUTISM, 2020; 11 (1)

Autism spectrum disorder (ASD) is a brain disorder that involves changes in neuronal connections. Abnormal morphology of dendritic spines on postsynap......

Autism prevalence in China is comparable to Western prevalence

期刊: MOLECULAR AUTISM, 2019; 10 ()

BackgroundAutism prevalence in the West is approximately 1% of school age children. Autism prevalence in China has been reported to be lower than in t......

JIF:5.71

The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism

期刊: MOLECULAR AUTISM, 2018; 9 ()

BackgroundGut microbiota has the capacity to impact the regular function of the brain, which can in turn affect the composition of microbiota. Autism ......

JIF:5.71

共25条页码: 1/2页15条/页