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Differentiation of different antifungals with various mechanisms using dynamic surface-enhanced Raman spectroscopy combined with machine learning

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (04)

With the increase in mortality caused by pathogens worldwide and the subsequent serious drug resistance owing to the abuse of antibiotics, there is an......

Determination of the immunoglobulin G precipitation end-point by an intelligent near-infrared spectroscopy system

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (03)

Precipitation is a key manufacturing unit during the immunoglobulin G (IgG) production, which guarantees the quality of the final product. Ethanol is ......

Construction of Au@Metal-organic framework for sensitive determination of creatinine in urine

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (04)

Creatinine level in urine is an important biomarker for renal function diseases, such as renal failure, glomerulonephritis, and chronic nephritis. The......

Binary organic nanoparticles with enhanced reactive oxygen species generation capability for photodynamic therapy

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (03)

Photodynamic therapy (PDT) takes advantage of photosensitizers (PSs) to generate reactive oxygen species (ROS) for cell killing when excited by light.......

Optical penetration of surface-enhanced micro-scale spatial offset Raman spectroscopy in turbid gel and biological tissue

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (04)

The limited penetration of photons in biological tissue restricts the deep-tissue detection and imaging application. The micro-scale spatially offset ......

Model eye tool for retinal optical coherence tomography instrument calibration

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (03)

Optical coherence tomography (OCT) has been extensively used as noninvasive tool for biological tissues owing to its three-dimensional imaging ability......

Availability and safety assessment of infrared neural stimulation at high repetition rate through an implantable optrode

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (03)

An implantable optrode with micro-thermal detectors was designed to investigate the availability and safety of INS using high repetition rates. Optica......

Simulation of stimulated Raman scattering signal generation in scattering tissues excited by Bessel beams

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (03)

Stimulated Raman scattering (SRS) microscopy has the ability of noninvasive imaging of specific chemical bonds and been increasingly used in biomedici......

In vivo evaluation of laser-induced choroidal neovascularization in rats simultaneously using optical coherence tomography and photoacoustic microscopy

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (03)

Determination of the precise location and the degree of the Choroidal neovascularization (CNV) lesion is essential for diagnosation Neovascular age-re......

Cytochrome-c aptamer functionalized Pt nanoclusters for enhanced chemodynamic therapy

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (04)

Catalysis-based chemodynamic therapy (CDT) is an emerging cancer treatment strategy which uses a Fenton-like reaction to kill tumor cells by catalyzin......

Surface-enhanced Raman spectroscopy of serum predicts sensitivity to docetaxel-based chemotherapy in patients with metastatic castration-resistant prostate cancer

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (04)

Docetaxel-based chemotherapy, as the first-line treatment for metastatic castration-resistant prostate cancer (mCRPC), has succeeded in helping quite ......

SERS devices with "hedgehog-like" nanosphere arrays for detection of trace pesticides

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (04)

The development of surface-enhanced Raman scattering (SERS) devices for detection of trace pesticides has attracted more and more attention. In this w......

Effects of stimulating frequency of NIR LEDs light irradiation on forehead as quantified by EEG measurements

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (2)

Near-infrared (NIR) light has been shown to produce a range of physiological effects in humans, however, there is still no agreement on whether and ho......

Structured illumination microscopy based on asymmetric three-beam interference

期刊: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2021; 14 (2)

Structured illumination microscopy (SIM) is a rapidly developing super-resolution technology. It has been widely used in various application fields of......

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