期刊: STATISTICS IN MEDICINE, 2021; 40 (17)
Heterogeneity is a hallmark of many complex diseases. There are multiple ways of defining heterogeneity, among which the heterogeneity in genetic regu......
期刊: STATISTICS IN MEDICINE, 2021; 40 (15)
We propose a multithreshold change plane regression model which naturally partitions the observed subjects into subgroups with different covariate eff......
期刊: STATISTICS IN MEDICINE, 2021; 40 (15)
Microbial communities analysis is drawing growing attention due to the rapid development fire of high-throughput sequencing techniques nowadays. The o......
期刊: STATISTICS IN MEDICINE, 2021; 40 (21)
Repeated measures are often collected in longitudinal follow-up from clinical trials and observational studies. In many situations, these measures are......
期刊: STATISTICS IN MEDICINE, 2021; 40 (17)
Mediation analysis is a useful tool in randomized trials for understanding how a treatment works, in particular how much of the treatment's effect on ......
期刊: STATISTICS IN MEDICINE, 2021; 40 (18)
Recurrent event data frequently arise in longitudinal studies and observations on recurrent events could be terminated by a major failure event such a......
期刊: STATISTICS IN MEDICINE, 2021; 40 (20)
Noncompliance issue is common in early phase clinical trials; and may lead to biased estimation of the intent-to-treat effect and incorrect conclusion......
期刊: STATISTICS IN MEDICINE, 2021; 40 (21)
This article proposes a powerful method to compare two samples. The proposed method handles comparison of data by drawing inference from ROC curve mod......
期刊: STATISTICS IN MEDICINE, 2021; 40 (18)
Bulk and single-cell RNA-seq (scRNA-seq) data are being used as alternatives to traditional technology in biology and medicine research. These data ar......
期刊: STATISTICS IN MEDICINE, 2021; 40 (15)
Alzheimer's disease can be diagnosed by analyzing brain images (eg, magnetic resonance imaging, MRI) and neuropsychological tests (eg, mini-mental sta......
期刊: STATISTICS IN MEDICINE, 2021; 40 (13)
In cancer studies, it is important to understand disease heterogeneity among patients so that precision medicine can particularly target high-risk pat......
期刊: STATISTICS IN MEDICINE, 2021; 40 (19)
Since the outbreak of the new coronavirus disease (COVID-19), a large number of scientific studies and data analysis reports have been published in th......
期刊: STATISTICS IN MEDICINE, 2021; 40 (15)
Promotion time cure rate models (PCM) are often used to model the survival data with a cure fraction. Medical images or biomarkers derived from medica......
期刊: STATISTICS IN MEDICINE, ; ()
We evaluate the validity of a projection-based test checking linear models when the number of covariates tends to infinity, and analyze two gene expre......
期刊: STATISTICS IN MEDICINE, ; ()
Motivated by inferring cellular signaling networks using noisy flow cytometry data, we develop procedures to draw inference for Bayesian networks base......