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Sea urchin gangliosides exhibit neuritogenic effects in neuronal PC12 cells via TrkA- and TrkB-related pathways

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (3)

Gangliosides (GLSs) are ubiquitously distributed in all tissues but highly enriched in nervous system. Currently, it is unclear how exogenous GLSs reg......

Arabidopsis CIB3 regulates photoperiodic flowering in an FKF1-dependent way

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (4)

Arabidopsis cryptochrome 2 (CRY2) and FLAVIN-BINDING, KELCH REPEAT, and F-BOX 1 (FKF1) are blue light receptors mediating light regulation of growth a......

COPS8 in cutaneous melanoma: an oncogene that accelerates the malignant development of tumor cells and predicts poor prognosis

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (2)

This study aimed to investigate the roles of COP9 signalosome subunit 8 (COPS8) and its underlying mechanism in cutaneous melanoma. Bioinformatics too......

Long noncoding RNA MNX1-AS1 functions as a competing endogenous RNA to regulate epithelial-mesenchymal transition by sponging MiR-744-5p in colorectal cancer

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (3)

Colorectal cancer (CRC) is the fourth most deadly cancer globally. Long noncoding RNA MNX1-AS1 has been proven to play a regulatory role in various hu......

The C-terminal of the alpha 1b-adreneroceptor is a key determinant for its structure integrity and biological functions

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (5)

The C-terminal of G protein-coupled receptors is now recognized as being important for G protein activation and signaling function. To detect the role......

Enhancing bile tolerance of Lactobacilli is involved in the hypolipidemic effects of liraglutide

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (6)

Liraglutide is an analog of human glucagon-like peptide-1 which play essential roles in regulation of glycolipid metabolism. To investigate role of la......

A simple strategy to monitor the temporal and spatial distribution of alkaloids in sacred lotus leaves

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (6)

Owing to the high degree of diversity of metabolite pools and complexity of spatial and temporal distributions within biological tissues, currently av......

Metabolomic analysis to elucidate the change of the n-3 polyunsaturated fatty acids in senescent osteoblasts

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (3)

Senile osteoporosis is a major public health concern, and yet, effective treatment methods do not exist. Herein, we used metabolomics to analyze the c......

Puerarin plays a protective role in chondrocytes by activating Beclin1-dependent autophagy

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (3)

Puerarin can protect chondrocytes, whereby ameliorating osteoarthritis. Puerarin also promotes autophagy. Autophagy maintains chondrocyte homeostasis.......

Effects of vacuum soaking on the hydration, steaming, and physiochemical properties of japonica rice

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (3)

Soaking is an essential step in the processing of various rice products. In this study, the influences of vacuum soaking on hydration, steaming, and p......

PADI4 mediates autophagy and participates in the role of ganoderic acid A monomers in delaying the senescence of Alzheimer's cells through the Akt/mTOR pathway

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (8)

The effects of PADI4 and GAA on the senescence of Alzheimer's cells were explored in the present work. HT22 cells were treated with A beta 25-35 to es......

Genome-wide association study reveals the genes associated with the leaf inclusion contents in Chinese medical tree Eucommia ulmoides

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (2)

Eucommia ulmoides is an economic tree that can biosynthesize secondary metabolites with pharmacological functions. Genetic basis of biosynthesis of th......

Long noncoding RNA ZFAS1 suppresses chondrocytes apoptosis via miR-302d-3p/SMAD2 in osteoarthritis

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (4)

Osteoarthritis (OA) seriously affects people's quality of life due to joint pain, stiffness, disability, and dyskinesia worldwide. Long noncoding RNA ......

Detection of 4 quinolone antibiotics by chemiluminescence based on a novel Nor-Biotin bifunctional ligand and SA-ALP technology

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (7)

A simple and effective direct competitive chemiluminescence immunoassay for the detection of 4 kinds of quinolone antibiotics in milk was established ......

Gastrodin attenuates lithium-pilocarpine-induced epilepsy by activating AMPK-mediated PPAR alpha in a juvenile rat model

期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021; 85 (4)

Gastrodin has shown the potential as an anticonvulsant. Epilepsy is a neurological disease with significant effects in children. In the current study,......

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