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Deciphering clock genes as emerging targets against aging

期刊: AGEING RESEARCH REVIEWS, 2022; 81 ()

The old people often suffer from circadian rhythm disturbances, which in turn accelerate aging. Many agingrelated degenerative diseases such as Alzhei......

JIF:10.078

Potential mechanisms underlying the accelerated cognitive decline in people with chronic low back pain: A scoping review

期刊: AGEING RESEARCH REVIEWS, 2022; 82 ()

A growing body of evidence has shown that people with chronic low back pain (CLBP) demonstrate significantly greater declines in multiple cognitive do......

JIF:10.078

Multi-omics research in sarcopenia: Current progress and future prospects

期刊: AGEING RESEARCH REVIEWS, 2022; 76 ()

Sarcopenia is a systemic disease with progressive and generalized skeletal muscle dysfunction defined by age-related low muscle mass, high content of ......

JIF:10.078

Adipose tissue spexin in physical exercise and age-associated diseases

期刊: AGEING RESEARCH REVIEWS, 2022; 73 ()

It is known that a strong association exists between a suboptimal lifestyle (physical inactivity and sedentary behavior and/or high calorie diet) and ......

JIF:10.078

The NLRP3 inflammasome in fibrosis and aging: The known unknowns

期刊: AGEING RESEARCH REVIEWS, 2022; 79 ()

Aging-related diseases such as cancer, cardiovascular diseases, diabetes, and neurodegenerative diseases are often accompanied by fibrosis. The NLRP3 ......

JIF:10.078

Formaldehyde toxicity in age-related neurological dementia

期刊: AGEING RESEARCH REVIEWS, 2022; 73 ()

The primordial small gaseous molecules, such as: NO, CO, H2S and formaldehyde (FA) are present in the brains. Whether FA as well as the other molecule......

JIF:10.078

Frailty in rodents: Models, underlying mechanisms, and management

期刊: AGEING RESEARCH REVIEWS, 2022; 79 ()

Frailty is a clinical geriatric syndrome characterized by decreased multisystem function and increased vulner-ability to adverse outcomes. Although nu......

JIF:10.078

Targeting small heat shock proteins to degrade aggregates as a potential strategy in neurodegenerative diseases

期刊: AGEING RESEARCH REVIEWS, 2022; 82 ()

Neurodegenerative diseases (NDs) are aging-related diseases that involve the death of neurons in the brain. Dysregulation of protein homeostasis leads......

JIF:10.078

Exosome: A novel neurotransmission modulator or non-canonical neurotransmitter?

期刊: AGEING RESEARCH REVIEWS, 2022; 74 ()

Neurotransmission is the electrical impulse-triggered propagation of signals between neurons or between neurons and other cell types such as skeletal ......

JIF:10.078

The role of nerve fibers and their neurotransmitters in regulating intervertebral disc degeneration

期刊: AGEING RESEARCH REVIEWS, 2022; 81 ()

Intervertebral disc degeneration (IVDD) has been the major contributor to chronic lower back pain (LBP). Abnormal apoptosis, senescence, and pyroptosi......

JIF:10.078

Physical resilience in older adults: Potential use in promoting healthy aging

期刊: AGEING RESEARCH REVIEWS, 2022; 81 ()

Physical resilience is a dynamic concept referring to the physiological response when the body is exposed to stressors. The level of physical resilien......

JIF:10.078

Association of kidney function and brain health: A systematic review and meta-analysis of cohort studies

期刊: AGEING RESEARCH REVIEWS, 2022; 82 ()

Objective: This study aimed to evaluate the bidirectional association between the kidney dysfunction and the brain health, including structural and fu......

JIF:10.078

Benefits of Tai Chi Quan on neurodegenerative diseases: A systematic review

期刊: AGEING RESEARCH REVIEWS, 2022; 82 ()

Background: Neurodegenerative diseases have become an important concern with the accelerated aging process. Tai Chi Quan (TCQ) has positive benefits f......

JIF:10.078

Emerging insights between gut microbiome dysbiosis and Parkinson?s disease: Pathogenic and clinical relevance

期刊: AGEING RESEARCH REVIEWS, 2022; 82 ()

Parkinson's disease (PD) is a complicated neurodegenerative disease, of which gastrointestinal disturbance ap-pears prior to motor symptoms. Numerous ......

JIF:10.078

Melatonin: A novel candidate for the treatment of osteoarthritis

期刊: AGEING RESEARCH REVIEWS, 2022; 78 ()

Osteoarthritis (OA), characterized by cartilage erosion, synovium inflammation, and subchondral bone remodeling, is a common joint degenerative diseas......

JIF:10.078

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