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Epigenetic gene regulation in plasma cells

期刊: IMMUNOLOGICAL REVIEWS, 2021; 303 (1)

Humoral immunity provides protection from pathogenic infection and is mediated by antibodies following the differentiation of naive B cells (nBs) to a......

Novel mechanisms and clinical trial endpoints in intestinal fibrosis*

期刊: IMMUNOLOGICAL REVIEWS, 2021; 302 (1)

The incidence of inflammatory bowel diseases (IBD) worldwide has resulted in a global public health challenge. Intestinal fibrosis leading to strictur......

The role of B cell antigen presentation in the initiation of CD4+T cell response

期刊: IMMUNOLOGICAL REVIEWS, 2020; 296 (1)

B cells have been known for their ability to present antigens to T cells for almost 40 years. However, the precise roles of B cell antigen presentatio......

Metabolic determinants of lupus pathogenesis

期刊: IMMUNOLOGICAL REVIEWS, 2020; 295 (1)

The metabolism of healthy murine and more recently human immune cells has been investigated with an increasing amount of details. These studies have r......

Nuclear innate sensors for nucleic acids in immunity and inflammation

期刊: IMMUNOLOGICAL REVIEWS, 2020; 297 (1)

Innate sensors recognize pathogen-associated molecular patterns (PAMPs) or damage-associated molecular patterns (DAMPs) to initiate innate immune resp......

Fast-acting gamma delta T-cell subpopulation and protective immunity against infections

期刊: IMMUNOLOGICAL REVIEWS, 2020; 298 (1)

Unique V gamma 2V delta 2 (V gamma 9V delta 2) T cells existing only in human and non-human primates, account for the majority of circulating gamma de......

T-FH cells in bystander and cognate interactions with B cells

期刊: IMMUNOLOGICAL REVIEWS, 2019; 288 (1)

Follicular T-helper (T-FH) cells play a crucial role in three aspects of the germinal center (GC) response. They promote GC formation, arbitrate compe......

JIF:11.29

A PI(4,5)P2-derived "gasoline engine model" for the sustained B cell receptor activation

期刊: IMMUNOLOGICAL REVIEWS, 2019; 291 (1)

To efficiently initiate activation responses against rare ligands in the microenvironment, lymphocytes employ sophisticated mechanisms involving signa......

JIF:11.29

Memory T-cell exhaustion and tolerance in transplantation

期刊: IMMUNOLOGICAL REVIEWS, 2019; 292 (1)

One of the biggest barriers to achieving allograft tolerance is the presence of immunological memory within the recipient, which confers a faster, mor......

JIF:11.29

Impact of infection on transplantation tolerance

期刊: IMMUNOLOGICAL REVIEWS, 2019; 292 (1)

Allograft tolerance is the ultimate goal of organ transplantation. Current strategies for tolerance induction mainly focus on inhibiting alloreactive ......

JIF:11.29

New checkpoints in cancer immunotherapy

期刊: IMMUNOLOGICAL REVIEWS, 2017; 276 (1)

Immune responses must be fine-tuned to allow effective clearance of invading pathogens, while maintain tolerance to self-antigens. T cells are the maj......

JIF:9.22

IL-25 in allergic inflammation

期刊: IMMUNOLOGICAL REVIEWS, 2017; 278 (1)

IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to th......

JIF:9.22

The renaissance of anti-neoplastic immunity from tumor cell demise

期刊: IMMUNOLOGICAL REVIEWS, 2017; 280 (1)

Cancer therapies can temporarily reduce tumor burdens by inducing malignant cell death. However, cancer cure is still far from realization because tum......

JIF:9.22

The metabolic characteristic of decidual immune cells and their unique properties in pregnancy loss

期刊: IMMUNOLOGICAL REVIEWS, 2022; 308 (1)

Maternal tolerance to semi- or fully allograft conceptus is a prerequisite for the maintenance of pregnancy. Once this homeostasis is disrupted, it ma......

JIF:11.603

Next generation of immune checkpoint molecules in maternal-fetal immunity

期刊: IMMUNOLOGICAL REVIEWS, 2022; 308 (1)

Successful pregnancy is a unique situation requires the maternal immune system to recognize and tolerate a semi-identical fetus and allow normal invas......

JIF:11.603

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