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Handheld bioprinting strategies for in situ wound dressing

期刊: 3D BIOPRINTING, 2021; 65 (3)

Handheld bioprinting has recently attracted considerable attention as a technology to deliver biomaterials and/or cells to injury sites by using freef......

Strategies for inclusion of growth factors into 3D printed bone grafts

期刊: 3D BIOPRINTING, 2021; 65 (3)

There remains a critical need to develop new technologies and materials that can meet the demands of treating large bone defects. The advancement of 3......

Laser-based bioprinting for multilayer cell patterning in tissue engineering and cancer research

期刊: 3D BIOPRINTING, 2021; 65 (3)

3D printing, or additive manufacturing, is a process for patterning functional materials based on the digital 3D model. A bioink that contains cells, ......

The Design-Build-Test-Learn cycle for metabolic engineering of Streptomycetes

期刊: MICROBIAL CELL FACTORIES-BOOK, 2021; 65 (2)

Streptomycetes are producers of a wide range of specialized metabolites of great medicinal and industrial importance, such as antibiotics, antifungals......

Production of proteins and commodity chemicals using engineered Bacillus subtilis platform strain

期刊: MICROBIAL CELL FACTORIES-BOOK, 2021; 65 (2)

Currently, increasing demand of biochemicals produced from renewable resources has motivated researchers to seek microbial production strategies inste......

Halomonas as a chassis

期刊: MICROBIAL CELL FACTORIES-BOOK, 2021; 65 (2)

With the rapid development of systems and synthetic biology, the non-model bacteria, Halomonas spp., have been developed recently to become a cost-com......

Microbial cell factories for the production of polyhydroxyalkanoates

期刊: MICROBIAL CELL FACTORIES-BOOK, 2021; 65 (2)

Pollution caused by persistent petro-plastics is the most pressing problem currently, with 8 million tons of plastic waste dumped annually in the ocea......

Construction and analysis of artificial chromosomes with de novo holocentromeres in Caenorhabditis elegans

期刊: KINETOCHORES AND CHROMOSOME SEGREGATION, 2020; 64 (2)

Artificial chromosomes (ACs), generated in yeast (YACs) and human cells (HACs), have facilitated our understanding of the trans-acting proteins, cis-a......

Detection methods of epitranscriptomic mark N-6-methyladenosine

期刊: SPOTLIGHT ON CHINA: RNA, 2020; 64 (6)

Research on N-6-methyladenosine (m(6)A) in recent years has revealed the complex but elegant regulatory role of this RNA modification in multiple phys......

Targeting RNA structures in diseases with small molecules

期刊: SPOTLIGHT ON CHINA: RNA, 2020; 64 (6)

RNA is crucial for gene expression and regulation. Recent advances in understanding of RNA biochemistry, structure and molecular biology have revealed......

microRNA regulation of pluripotent state transition

期刊: SPOTLIGHT ON CHINA: RNA, 2020; 64 (6)

microRNAs (miRNAs) play essential roles in mouse embryonic stem cells (ESCs) and early embryo development. The exact mechanism by which miRNAs regulat......

Processing of coding and non-coding RNAs in plant development and environmental responses

期刊: SPOTLIGHT ON CHINA: RNA, 2020; 64 (6)

Precursor RNAs undergo extensive processing to become mature RNAs. RNA transcripts are subjected to 5' capping, 3'-end processing, splicing, and modif......

The diversity of post-transcriptional gene silencing mediated by small silencing RNAs in plants

期刊: SPOTLIGHT ON CHINA: RNA, 2020; 64 (6)

In plants, post-transcriptional gene silencing (PTGS) tightly regulates development, maintains genome stability and protects plant against foreign gen......

An emerging role of chromatin-interacting RNA-binding proteins in transcription regulation

期刊: SPOTLIGHT ON CHINA: RNA, 2020; 64 (6)

Transcription factors (TFs) are well-established key factors orchestrating gene transcription, and RNA-binding proteins (RBPs) are mainly thought to p......

Out or decay: fate determination of nuclear RNAs

期刊: SPOTLIGHT ON CHINA: RNA, 2020; 64 (6)

In eukaryotes, RNAs newly synthesized by RNA polymerase II (RNAPII) undergo several processing steps prior to transport to the cytoplasm. It has long ......

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