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Invaginating Structures in Synapses - Perspective

期刊: FRONTIERS IN SYNAPTIC NEUROSCIENCE, 2021; 13 ()

Invaginating structures are common in the synapses of most animals. However, the details of these invaginating structures remain understudied in part ......

Diverse organization of voltage-gated calcium channels at presynaptic active zones

期刊: FRONTIERS IN SYNAPTIC NEUROSCIENCE, 2022; 14 ()

Synapses are highly organized but are also highly diverse in their organization and properties to allow for optimizing the computing power of brain ci......

Astrocyte: A Foe or a Friend in Intellectual Disability-Related Diseases

期刊: FRONTIERS IN SYNAPTIC NEUROSCIENCE, 2022; 14 ()

Intellectual disabilities are a type of neurodevelopmental disease caused by neurological dysfunction. Their incidence is largely associated with neur......

Dexmedetomidine and Ketamine Attenuated Neuropathic Pain Related Behaviors via STING Pathway to Induce ER-Phagy

期刊: FRONTIERS IN SYNAPTIC NEUROSCIENCE, 2022; 14 ()

Our previous work indicated that ER-phagy level had altered in spinal nerve ligation (SNL) rats. In this study, we investigated whether dexmedetomidin......

The biological alterations of synapse/synapse formation in sepsis-associated encephalopathy

期刊: FRONTIERS IN SYNAPTIC NEUROSCIENCE, 2022; 14 ()

Sepsis-associated encephalopathy (SAE) is a common complication caused by sepsis, and is responsible for increased mortality and poor outcomes in sept......

Different Synaptic Plasticity After Physiological and Psychological Stress in the Anterior Insular Cortex in an Observational Fear Mouse Model

期刊: FRONTIERS IN SYNAPTIC NEUROSCIENCE, 2022; 14 ()

Post-traumatic stress disorder (PTSD) can be triggered not only in people who have personally experienced traumatic events but also in those who witne......

Glucagon-like peptide 1 and glucose-dependent insulinotropic peptide hormones and novel receptor agonists protect synapses in Alzheimer's and Parkinson's diseases

期刊: FRONTIERS IN SYNAPTIC NEUROSCIENCE, 2022; 14 ()

Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) are peptide hormones and growth factors. A major pathological featu......

Correlative Assembly of Subsynaptic Nanoscale Organizations During Development

期刊: FRONTIERS IN SYNAPTIC NEUROSCIENCE, 2022; 14 ()

Nanoscale organization of presynaptic proteins determines the sites of transmitter release, and its alignment with assemblies of postsynaptic receptor......

Towards a Comprehensive Optical Connectome at Single Synapse Resolution via Expansion Microscopy

期刊: FRONTIERS IN SYNAPTIC NEUROSCIENCE, 2022; 13 ()

Mapping and determining the molecular identity of individual synapses is a crucial step towards the comprehensive reconstruction of neuronal circuits.......

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