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Efficacy of antidepressant drugs in the treatment of depression in Alzheimer disease patients: A systematic review and network meta-analysis

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2021; 35 (8)

Background: Depression is considered as one of the most common neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) patients. Prescription of a......

Pharmacological treatment for Tourette syndrome in children and adults: What is the quality of the evidence? A systematic review

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2021; 35 (9)

Background: Tourette syndrome (TS) is a neurodevelopmental disorder characterised by involuntary muscle movements manifesting as motor and vocal tics.......

Efficacy and tolerability of pharmacological interventions on metabolic disturbance induced by atypical antipsychotics in adults: A systematic review and network meta-analysis

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2021; 35 (9)

Background: There have been a few systematic reviews and conventional meta-analyses reporting effect of drugs on metabolic disturbance induced by atyp......

An efficient and label-free LC-MS/MS method for assessing drug's activity at dopamine and serotonin transporters using transporter-transfected HEK293T cells

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2021; 35 (6)

Background: Dopamine transporter (DAT) and serotonin transporter (SERT) are targets for many psychoactive substances. Functional assays including upta......

Intranasal oxytocin may help maintain romantic bonds by decreasing jealousy evoked by either imagined or real partner infidelity

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, ; ()

Background: While romantic jealousy may help to maintain relationships, following partner infidelity and an irretrievable loss of trust it can also pr......

Projection-specific dopamine neurons in the ventral tegmental area participated in morphine-induced hyperalgesia and anti-nociceptive tolerance in male mice

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, ; ()

Background: Long-term morphine use is associated with serious side effects, such as morphine-induced hyperalgesia and analgesic tolerance. Previous in......

Plasma d-glutamate levels for detecting mild cognitive impairment and Alzheimer's disease: Machine learning approaches

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2021; 35 (3)

Background: d-glutamate, which is involved in N-methyl-d-aspartate receptor modulation, may be associated with cognitive ageing. Aims: This study aime......

Oxytocin-induced facilitation of learning in a probabilistic task is associated with reduced feedback- and error-related negativity potentials

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2021; 35 (1)

Background: Feedback evaluation of actions and error response detection are critical for optimizing behavioral adaptation. Oxytocin can facilitate lea......

MicroRNA-195 predicts olanzapine response in drug-free patients with schizophrenia: A prospective cohort study

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2021; 35 (1)

Background: Disturbances of microRNA-195 have been implicated in the pathogenesis of schizophrenia. However, microRNA-195 levels in schizophrenia are ......

Body mass index as a determinant of clozapine plasma concentrations: A pharmacokinetic-based hypothesis

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2021; 35 (3)

Background: Knowledge regarding the impact of body composition measures on pharmacokinetics of antipsychotics is limited. Aims: Our aim was to investi......

Translocator protein-mediated fast-onset antidepressant-like and memory-enhancing effects in chronically stressed mice

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2020; 34 (4)

Background: Fast-acting and cognitive-enhancing antidepressants are desperately needed. Activation of translocator protein (18 kDa, TSPO) is a novel s......

Efficacy and cognitive effect of sarcosine (N-methylglycine) in patients with schizophrenia: A systematic review and meta-analysis of double-blind randomised controlled trials

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2020; 34 (5)

Background: Sarcosine (N-methylglycine), a type 1 glycine transporter inhibitor (GlyT1), has shown therapeutic potential for treating schizophrenia; h......

Melanin-concentrating hormone in rat nucleus accumbens or lateral hypothalamus differentially impacts morphine and food seeking behaviors

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2020; 34 (4)

Background: Identifying neural substrates that are differentially affected by drugs of abuse and natural rewards is key to finding a target for an eff......

trans-Resveratrol ameliorates anxiety-like behaviors and neuropathic pain in mouse model of post-traumatic stress disorder

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2020; 34 (7)

Background: trans-Resveratrol has been extensively investigated for its anti-inflammatory, antioxidant, and anti-psychiatric properties. However, whet......

An acetylcholinesterase inhibitor, donepezil, increases anxiety and cortisol levels in adult zebrafish

期刊: JOURNAL OF PSYCHOPHARMACOLOGY, 2020; 34 (12)

Background: A potent acetylcholinesterase inhibitor, donepezil is a cognitive enhancer clinically used to treat neurodegenerative diseases. However, i......

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