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Sauchinone inhibits hypoxia-induced invasion and epithelial-mesenchymal transition in osteosarcoma cells via inactivation of the sonic hedgehog pathway

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Hypoxia is a typical feature of solid tumors and is closely associated with tumor progression. Sauchinone, a biologically diastereomeric lignan, is is......

Baicalin suppresses the progression of preeclampsia via regulating miR-155-5p/FOXO3 axis

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Purpose: Baicalin is a favonoid monomer that is extracted from Scutellaria baicalensis Georgi. Previous studies reported its diverse pharmacological p......

Silencing of circular RNA PUM1 inhibits clear cell renal cell carcinoma progression through the miR-340-5p/FABP7 axis

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Circular RNAs (circRNAs) monitor the development of clear cell renal cell carcinoma (ccRCC). However, the role of CircPUM1 in ccRCC malignancy is not ......

Catestatin enhances ATP-induced activation of glial cells mediated by purinergic receptor P2X(4)

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

The activation of glial cells and its possible mechanism play an extremely important role in understanding the pathophysiological process of some clin......

Inhibition of TGF-beta 1 on Gli2 expression was promoted by TNF-alpha in primary leukemia cells

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Purpose Hedgehog (Hh) signaling pathway regulates a variety of tumors-related diseases including leukemia. Whether inhibition of TGF-beta 1 on Gli2 ex......

Polygonatum sibiricum polysaccharide inhibits high glucose-induced oxidative stress, inflammatory response, and apoptosis in RPE cells

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Diabetic retinopathy is one of the major diabetic complications and remains the most common cause of adult blindness among patients with diabetes mell......

Upregulation of SDHA inhibited proliferation, migration, and invasion of clear cell renal cell carcinoma cells via inactivation of the Wnt/beta-catenin pathway

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Clear cell renal cell carcinoma (ccRCC) is a common genitourinary malignancy with high mortality. Recent findings suggest that the succinate dehydroge......

Ultrasound microbubble-mediated miR-150-5p inhibits gastric cancer cell growth by targeting the expression of NR2F2

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Purpose Gastric cancer has a high mortality. MiR-150-5p and NR2F2 are related to gastric cancer and have a targeted relationship. Ultrasonic microbubb......

JAK2/STAT3 inhibitor reduced 5-FU resistance and autophagy through ATF6-mediated ER stress

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Drug resistance seriously limits the efficacy of chemotherapy drugs and hinders successful treatment in patients with gastric cancer. Endoplasmic reti......

Baicalin attenuates XRCC1-mediated DNA repair to enhance the sensitivity of lung cancer cells to cisplatin

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Baicalin plays important roles in different types of cancer. A previous report showed that baicalin attenuates cisplatin resistance in lung cancer. Ho......

FAM19A5/S1PR1 signaling pathway regulates the viability and proliferation of mantle cell lymphoma

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Several intracellular pathological processes have been reported to be regulated by the FAM19A5/S1PR1 signaling pathway. However, the role of FAM19A5/S......

Baicalin regulates the development of pediatric asthma via upregulating microRNA-103 and mediating the TLR4/NF-kappa B pathway

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Pediatric asthma seriously endangers the well-being and health of children worldwide. Baicalin (BA) protects against diverse disorders, including asth......

Inhibition of TRIM14 protects cerebral ischemia/reperfusion injury through regulating NF-kappa B/NLRP3 pathway-mediated inflammation and apoptosis

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, ; ()

Purpose: Many proteins in tripartite motif (TRIM) family have been reported to play an important role in cerebral ischemia/reperfusion (I/R) injury. T......

Dynamin-related protein-1 promotes lung cancer A549 cells apoptosis through the F-actin/bax signaling pathway

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2020; 40 (5)

Dynamin-related protein-1 (Drp1) has been found to be associated with cell death. The role of Drp1 in A549 cells death has not been explored. In this ......

Hesperidin promotes differentiation of alveolar osteoblasts via Wnt/beta-Catenin signaling pathway

期刊: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2020; 40 (5)

Alveolar bone has a high plasticity. The health of alveolar bones directly determines the success of oral implant surgery, and the health and function......

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