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Phenytoin Regulates Migration and Osteogenic Differentiation by MAPK Pathway in Human Periodontal Ligament Cells

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2022; 15 (1)

Introduction Periodontal healing requires an adequate number of periodontal ligament (PDL) cells to rebuild the impaired tissue. Phenytoin (PHT) has b......

JIF:2.012

Structural Mapping of BMP Conformational Epitopes and Bioengineering Design of Osteogenic Peptides to Specifically Target the Epitope-Binding Sites

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2022; 15 (4)

Introduction-Human bone morphogenetic proteins (BMPs) constitute a large family of cytokines related to members of the transforming growth factor-beta......

JIF:2.012

LINC00852 Regulates Cell Proliferation, Invasion, Migration and Apoptosis in Hepatocellular Carcinoma Via the miR-625/E2F1 Axis

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2022; 15 (2)

Objective This study investigates the function and regulatory mechanism of lncRNA LINC00852 in hepatocellular carcinoma (HCC) cells. Methods The effec......

JIF:2.012

Sevoflurane Suppresses the Proliferation, Migration and Invasion of Colorectal Cancer Through Regulating Circ_0000423/miR-525-5p/SGPP1 Network

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2022; 15 (2)

Introduction Sevoflurane (SEV) has been shown to inhibit the malignant progression in many cancers, including colorectal cancer (CRC). However, it is ......

JIF:2.012

Oral Administration of Cryptotanshinone-Encapsulated Nanoparticles for the Amelioration of Ulcerative Colitis

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2022; 15 (1)

Background Inappropriate macrophages phenotype transition contributes to the development of ulcerative colitis, and the poly (ethylene glycol)-block-p......

JIF:2.012

OTUB2 Promotes Proliferation and Migration of Hepatocellular Carcinoma Cells by PJA1 Deubiquitylation

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2022; 15 (3)

Introduction Recent studies have revealed that several deubiquitinating enzymes (DUBs) play important roles in hepatocellular carcinoma (HCC) progress......

JIF:2.012

Light Activates Cdc42-Mediated Needle-Shaped Filopodia Formation via the Integration of Small GTPases

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2022; 15 (6)

Introduction Cdc42 has been linked to multiple human cancers and is implicated in the migration of cancer cells. Cdc42 could be activated via biochemi......

JIF:2.012

Exosomes from Adipose Tissues Derived Mesenchymal Stem Cells Overexpressing MicroRNA-146a Alleviate Diabetic Osteoporosis in Rats

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2022; 15 (1)

Background Inflammation is one of major contributors of diabetic osteoporosis. Here, we combined adipose tissues derived mesenchymal stem cells (AD-MS......

JIF:2.012

miR-140-5p Overexpression Protects Against Lipopolysaccharide-Induced Necrotizing Pneumonia via Targeting Toll-Like Receptor 4

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2021; 14 (4)

Objective This study is to identify the effects of miRNA-140-5p on necrotizing pneumonia (NP) and its underlying mechanism. Methods The mRNA levels of......

General Characteristics of Microbubble-Adenovirus Vectors Carrying Genes

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2021; 14 (2)

Introduction-Transferring genes safely, targeting cells and achieving efficient transfection are urgent problems in gene therapy that need to be solve......

A Stereological Study of Mouse Ovary Tissues for 3D Bioprinting Application

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, ; ()

Introduction The use of 3D-bioprinted ovaries has been proven to be a promising technique for preserving fertility. Stereology is an accurate method t......

Engineered Aptamers for Enhanced COVID-19 Theranostics

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, ; ()

Introduction-The 2019-novel coronavirus disease (COVID-19) is an intractable global health challenge resulting in an aberrant rate of morbidity and mo......

Tissue Targeting and Ultrasound-Targeted Microbubble Destruction Delivery of Plasmid DNA and Transfection In Vitro

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2020; 13 (1)

Introduction Ultrasound-targeted microbubble destruction (UTMD) has been shown a promising approach for target-specific gene delivery and treatment of......

Early Intervention in Ischemic Tissue with Oxygen Nanocarriers Enables Successful Implementation of Restorative Cell Therapies

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2020; 13 (5)

Background Tissue ischemia contributes to necrosis and infection. While angiogenic cell therapies have emerged as a promising strategy against ischemi......

SIRT1 Inhibits High Shear Stress-Induced Apoptosis in Rat Cortical Neurons

期刊: CELLULAR AND MOLECULAR BIOENGINEERING, 2020; 13 (6)

Introduction Sirtuin1 (SIRT1), one of NAD(+)-dependent protein deacetylases, is proved to be neuroprotective in aging diseases, but its effect on neur......

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