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Cancer cells corrupt normal epithelial cells through miR-let-7c-rich small extracellular vesicle-mediated downregulation of p53/PTEN

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

Tumor volume increases continuously in the advanced stage, and aside from the self-renewal of tumor cells, whether the oncogenic transformation of sur......

JIF:5.8

Disrupted tenogenesis in masseter as a potential cause of micrognathia

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

Micrognathia is a severe craniofacial deformity affecting appearance and survival. Previous studies revealed that multiple factors involved in the ost......

JIF:5.8

Targeted inhibition of osteoclastogenesis reveals the pathogenesis and therapeutics of bone loss under sympathetic neurostress

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

Sympathetic cues via the adrenergic signaling critically regulate bone homeostasis and contribute to neurostress-induced bone loss, but the mechanisms......

JIF:5.8

A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

The positive regulation of bone-forming osteoblast activity and the negative feedback regulation of osteoclastic activity are equally important in str......

JIF:5.8

METTL3-mediated m(6)A RNA methylation regulates dorsal lingual epithelium homeostasis

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

The dorsal lingual epithelium, which is composed of taste buds and keratinocytes differentiated from K14(+) basal cells, discriminates taste compounds......

JIF:5.8

Metformin can mitigate skeletal dysplasia caused by Pck2 deficiency

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

As an important enzyme for gluconeogenesis, mitochondrial phosphoenolpyruvate carboxykinase (PCK2) has further complex functions beyond regulation of ......

JIF:5.8

Microenvironmental stiffness mediates cytoskeleton re-organization in chondrocytes through laminin-FAK mechanotransduction

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

Microenvironmental biophysical factors play a fundamental role in controlling cell behaviors including cell morphology, proliferation, adhesion and di......

JIF:5.8

circ_0003204 regulates the osteogenic differentiation of human adipose-derived stem cells via miR-370-3p/HDAC4 axis

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

Human adipose-derived stem cells (hASCs) are a promising cell type for bone tissue regeneration. Circular RNAs (circRNAs) have been shown to play a cr......

JIF:5.8

The role of dendritic cells in the immunomodulation to implanted biomaterials

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

Considering the substantial role played by dendritic cells (DCs) in the immune system to bridge innate and adaptive immunity, studies on DC-mediated i......

JIF:5.8

Extrapolating neurogenesis of mesenchymal stem/stromal cells on electroactive and electroconductive scaffolds to dental and oral-derived stem cells

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

The high neurogenic potential of dental and oral-derived stem cells due to their embryonic neural crest origin, coupled with their ready accessibility......

JIF:5.8

Tetrahedral framework nucleic acid carrying angiogenic peptide prevents bisphosphonate-related osteonecrosis of the jaw by promoting angiogenesis

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

The significant clinical feature of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is the exposure of the necrotic jaw. Other clinical manife......

JIF:5.8

Difficult and complicated oral ulceration: an expert consensus guideline for diagnosis

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

The complexity of oral ulcerations poses considerable diagnostic and therapeutic challenges to oral specialists. The expert consensus was conducted to......

JIF:5.8

Exosomes rewire the cartilage microenvironment in osteoarthritis: from intercellular communication to therapeutic strategies

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by cartilage loss and accounts for a major source of pain and disability w......

JIF:5.8

Expert consensus on dental caries management

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

Dental Caries is a kind of chronic oral disease that greatly threaten human being's health. Though dentists and researchers struggled for decades to c......

JIF:5.8

Periodontitis may induce gut microbiota dysbiosis via salivary microbiota

期刊: INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2022; 14 (1)

The aim of this study was to identify whether periodontitis induces gut microbiota dysbiosis via invasion by salivary microbes. First, faecal and sali......

JIF:5.8

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