期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2021; 26 (5)
Solidification of self-microemulsifying drug delivery systems (SMEDDS) is one of the major trends to promote the transformation of self-microemulsion ......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2021; 26 (5)
This study investigated the efficiency and the related mechanisms of a new absorption enhancer, DL-malic acid (MA), on the oral bioavailability of doc......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2021; 26 (7)
This work mainly studies the interfacial behaviors of scutellarin on a newly developed emulsion and establishes a three-phase distribution model. The ......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2021; 26 (8)
Curcumin (CUR) shows great potential in the management of alcohol-use disorders. However, the hydrophobicity and poor oral bioavailability result in t......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2021; 26 (8)
Polycaprolactone-poly (ethylene glycol) block copolymer (PCL-PEG) based nanoparticles were prepared for the intravenous administration of docetaxel (D......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2021; 26 (6)
A combination of doxorubicin (DOX) and small interfering RNA (siRNA) is proven effective for the reverse of multidrug resistance. However, rapid degra......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2021; 26 (1)
Nanostructured lipid carriers (NLC) have become a research hotspot, wherein cancer-targeting effects are enhanced and side effects of chemotherapy are......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2021; 26 (3)
Hypertension is one of the most common chronic cardiovascular disorders. Sustained-release formulations are developed to maintain drug therapeutic lev......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2020; 25 (1)
6-Gingerol, an active herbal ingredient of ginger has various bioactivities such as anti-neurodegenerative disease, anti-inflammatory and so on. The a......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2020; 25 (3)
Curcumin, a polyphenol compound extracted from the roots of turmeric plants, possesses anti-depressant effect by regulating the levels of neuroendocri......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2019; 24 (1)
A bilayered mucoadhesive buccal film containing a combination of ornidazole (OD) and dexamethasone sodium phosphate (DEX) was prepared using solvent c......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2019; 24 (2)
The key for better antitumor efficacy is to improve the specificity of antitumor drugs for tumor cells and diminish their cytotoxicity to normal tissu......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2019; 24 (5)
The aim of this study was to investigate intravitreal injection of silk fibroin nanoparticles (SFNs) encapsulating bio-macromolecules, achieving enhan......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2019; 24 (4)
Reliable monitoring of solution crystallization processes is important to provide further insight into process dynamics and to improve process control......
期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2019; 24 (4)
Recombinant human growth hormone (rhGH) therapy must be administered as a daily injection due to its short half-life. To achieve sustained release of ......