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Fluorofenidone inhibits epithelial-mesenchymal transition in human lens epithelial cell line FHL 124: a promising therapeutic strategy against posterior capsular opacification

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2021; 84 (3)

Purpose: The present study aimed to investigate the inhibitory effect of fluorofenidone against transforming growth factor beta 2-induced proliferatio......

High glucose induces pyroptosis of retinal microglia through NLPR3 inflammasome signaling

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2021; 84 (1)

Purpose: Diabetic retinopathy is currently considered a chronic inflammatory disease involving NOD-like receptor family pyrin domain containing 3 infl......

Firearm-associated ocular injuries: analysis of national trauma data

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2021; 84 (1)

Purpose: The United States of America has the highest gun ownership rate of all high-income nations, and firearms have been identified as a leading ca......

Corneal differences between healthy and subclinical patients assessed using two different corneal tomographers

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2020; 83 (2)

Purpose: To analyze subclinical keratoconus topography indexes using Pentacam and Orbscan-II measurements to identify evidences for seeking sensitive ......

Dynamic changes of periostin and collagen I in the sclera during progressive myopia in guinea pigs

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2020; 83 (3)

Purpose: To investigate periostin and collagen I expression during a scleral remodeling in myopic eyes and to determine their role in collagen remodel......

Anti-fibrotic effects of rosmarinic acid on Tenon's capsule fibroblasts stimulated with TGF-beta: therapeutic potential in ocular surgery

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2020; 83 (4)

Purpose: Collagen deposition and myofibroblast differentiation are critical factors related to excessive scarring in ocular surgeries. This study eval......

Impact of different clear corneal incision sizes on anterior corneal aberration for cataract surgery

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2020; 83 (6)

Purpose: To investigate the impact of different sizes of steep meridian clear corneal incisions for phacoemulsification on anterior corneal higher-ord......

Evaluation of three superior oblique surgical weakening procedures for A-pattern strabismus

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2019; 82 (5)

Purpose: To evaluate three superior oblique surgical weakening procedures for correcting A-pattern strabismus: tenectomy, superior oblique hang-back r......

JIF:0.86

Expression of specificity protein 1 and collagen I in primary pterygial tissues

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2019; 82 (5)

Purpose: To determine the expression profiles of the transcription factor specificity protein 1 and collagen I in primary pterygial and normal conjunc......

JIF:0.86

Long-term treatment with 3,4-methylenedioxymethamphetamine caused retina damage in C57BL/6 mice

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2019; 82 (5)

Purpose: As a class of psychostimulant drugs, amphetamines are widely abused for their stimulant, euphoric, and hallucinogenic properties. Many of the......

JIF:0.86

Prostaglandin antagonist relieves blood-retinal barrier breakdown induced by anterior segment intraocular surgery in a rat model

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2018; 81 (3)

Purpose: To evaluate the efficacy of prostaglandin antagonists on blood-retinal barrier breakdown induced by anterior segment intraocular simulated su......

JIF:0.86

Induction of pluripotent stem cells by reprogramming human ocular fibroblasts under xeno-free conditions

期刊: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, 2018; 81 (5)

Purposes: To develop an efficient and xeno-free standard eye-derived induced pluripotent stem cell reprogramming protocol for use during induced pluri......

JIF:0.86

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