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Decidual cells are the initial target of polyriboinosinic-polyribocytidylic acid in a mouse model of maternal viral infection

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 26 ()

Background: Maternal immune activation has been implicated in the pathophysiology of neurodevelopmental disorders such as autism spectrum disorders ca......

Adlay hull extracts attenuate beta-amyloid-induced neurotoxicity and oxidative stress in PC12 cells through antioxidative, anti-inflammatory, and antiapoptotic activities

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 26 ()

Alzheimer's disease (AD) is characterized by accumulation of beta-amyloid (A beta) in senile plaques, contributing to oxidative stress, mitochondrial ......

MicroRNA-21 facilitates osteoblast activity

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 25 ()

MicroRNAs are emerging as critical post-transcriptional modulators in bone remodeling, regulating the functions of osteoblasts and osteoclasts. Interc......

G protein and PLD delta are involved in JA to regulate osmotic stress responses in Arabidopsis thaliana

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 26 ()

Jasmonic acid (JA) is regarded as an endogenous regulator which plays an important role in regulating plant growth, development and stress response. U......

Biochemical properties of a native beta-1,4-mannanase from Aspergillus aculeatus QH1 and partial characterization of its N-glycosylation

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 26 ()

N-glycosylation plays critical roles in protein secretion, sorting, stability, activity modulation, and interactions to other molecules in the eukaryo......

Dendrobium nobile Lindl. alkaloids alleviate Mn-induced neurotoxicity via PINK1/Parkin-mediated mitophagy in PC12 cells

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 26 ()

Modern pharmacological studies have demonstrated that Dendrobium nobile Lindl. Alkaloids (DNLA), the main active ingredients of Dendrobium nobile, is ......

Cancer spheroids derived exosomes reveal more molecular features relevant to progressed cancer

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 26 ()

Cancer cell spheroids have been shown to be more physiologically relevant to native tumor tissue than monolayer 2D culture cells. Due to enhanced inte......

Protein tyrosine phosphatase receptor type E (PTPRE) regulates the activation of wild-type KIT and KIT mutants differently

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 26 ()

Activation of receptor tyrosine kinases needs tight control by tyrosine phosphatases to keep their normal function. In this study, we investigated the......

The study of gp130/the inflammatory factors regulating osteoclast differentiation in rheumatoid arthritis

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 26 ()

Rheumatoid arthritis (RA) is a chronic immune disease characterized by synovitis and bone destruction. The osteoclasts play a critical role in patholo......

Toxicity of gold nanoparticles (AuNPs): A review

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 26 ()

Gold nanoparticles are a kind of nanomaterials that have received great interest in field of biomedicine due to their electrical, mechanical, thermal,......

Is there a correlation between miR-301a expression and neoadjuvant chemotherapy efficacy in breast cancer tissue?

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 26 ()

Neoadjuvant chemotherapy (NAC) is the standard therapeutic regimen for locally advanced breast cancer. However, clinical physical examination and imag......

A high methionine and low folate diet alters glucose homeostasis and gut microbiome

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 25 ()

Hyperhomocysteinemia (HHcy) is considered as a risk factor for several complications, including cardiovascular and neurological disorders. A high meth......

Quantitative analysis of carnosine, anserine, and homocarnosine in skeletal muscle of aquatic species from east China sea

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2021; 25 ()

Y Histidine-containing dipeptides (HCDs) are a family of non-protein, nitrogen-containing compounds with multiple physiological roles and are mainly p......

Roles of Ca2+ activity in injury-induced migration of microglia in zebrafish in vivo

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2022; 32 ()

Microglia are the resident immune cells in the brain. It is well known that brain injury can activate the microglia and induce its directional migrati......

Esophageal squamous cell carcinoma: Integrated bioinformatics analysis for differential gene expression with identification of hub genes and lncRNA

期刊: BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2022; 30 ()

Background: Esophageal squamous cell carcinoma (ESCC) is a typical Gastro-Intestinal (GI) tract neoplasm. This study was conducted to know the Differe......

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