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The clinical application of SNP-based next-generation sequencing (SNP-NGS) for evaluation of chimerism and microchimerism after HLA-mismatched stem cell microtransplantation

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 116 (5)

Genetic diagnostic methods for evaluation of chimerism after HSCT, such as STR-PCR and XY-FISH, have limited sensitivity. When donor chimerism is in t......

JIF:1.859

Post-remission measurable residual disease directs treatment choice and improves outcomes for patients with intermediate-risk acute myeloid leukemia in CR1

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 116 (6)

Objectives This study retrospectively investigated in which cycle measurable residual disease (MRD) is associated with prognosis in patients in first ......

JIF:1.859

Mutational landscape of chronic myelomonocytic leukemia and its potential clinical significance

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 115 (1)

We evaluated the mutational landscape of chronic myelomonocytic leukemia (CMML) and its potential clinical significance. We analyzed 47 samples with a......

JIF:1.859

Decitabine combined with minimally myelosuppressive therapy for induction of remission in pediatric high-risk acute myeloid leukemia with chromosome 5q deletion: a report of three cases

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 116 (1)

Cases of pediatric acute myeloid leukemia (AML) with complex karyotypes including chromosome 5 abnormalities are rare and have a very poor prognosis. ......

JIF:1.859

A retrospective single-center analysis of G-CSF-mobilized donor lymphocyte infusion in hematologic malignancies after unmanipulated allogenic PBSCT

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 115 (5)

To explore the efficacy and safety of G-SCF-mobilized donor lymphocyte infusion (DLI) for treatment of relapse of hematologic malignancies after allog......

JIF:1.859

Propensity score matching/reweighting analysis comparing autologous and allogeneic stem cell transplantation for B-lineage acute lymphoblastic leukemia

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 116 (3)

We compared the outcomes of autologous stem cell transplantation (auto-SCT) with those of allogeneic stem cell transplantation (allo-SCT) from a human......

JIF:1.859

NUDT15 genetic testing-guided 6-mercaptopurine dosing in children with ALL likely to be cost-saving in China

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 115 (2)

Objective The cost-effectiveness of NUDT15 genetic testing-guided initial 6-mercaptopurine (6-MP) dosing in children with acute lymphoblastic leukemia......

JIF:1.859

Droplet digital PCR for genetic mutations monitoring predicts relapse risk in pediatric acute myeloid leukemia

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 116 (5)

Multiparameter flow cytometry (MFC)-based minimal residual disease has been a poor predictor of prognosis in children with acute myeloid leukemia (AML......

JIF:1.859

Companion gene mutations and their clinical significance in AML with double or single mutant CEBPA

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 116 (1)

Introduction We report the co-mutations in AML with CEBPA(sm) or CEBPA(dm) and their clinical features in a large cohort (n = 302) of CEBPA(mut) AML p......

JIF:1.859

Prognostic impacts of serum levels of C-reactive protein, albumin, and total cholesterol in patients with myelodysplastic syndromes

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 116 (1)

Various systems for predicting the prognosis of patients with myelodysplastic syndromes (MDS) have been developed. However, associations between perfo......

JIF:1.859

Adverse impact of a high allelic burden FLT3-ITD mutation on allogeneic hematopoietic stem cell transplantation in patients with cytogenetically normal AML

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022; 116 (5)

Risks associated with the FLT3-ITD mutation in patients receiving chemotherapy alone for cytogenetic normal acute myeloid leukemia (CN-AML) depend on ......

JIF:1.859

Compound heterozygosity for two novel mutations of the SEC23B gene in congenital dyserythropoietic anemia type II

期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY, 2021; 114 (3)

Congenital dyserythropoietic anemia type II (CDA II), a rare genetic disorder, results from SEC23B gene mutations according to previous studies. Here,......

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