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Histone deacetylase 3 (HDAC3) as an important epigenetic regulator of kidney diseases

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (1)

Development and progression of many kidney diseases are substantially influenced by aberrant protein acetylation modifications of gene expression cruc......

JIF:4.403

The vasculature niches required for hematopoiesis

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (1)

Endothelial cells play a critical role in supporting postnatal hematopoiesis in the bone marrow. Unique endothelial cells, together with various periv......

JIF:4.403

Targeting the Wnt signaling pathway for breast cancer bone metastasis therapy

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (3)

Osteolytic bone destruction is found in approximately 60% of advanced breast cancer patients. With the pathogenesis of bone metastasis being unclear, ......

JIF:4.403

Underlying mechanisms of epithelial splicing regulatory proteins in cancer progression

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (11)

Cancer is the second-leading disease-related cause of global mortality after cardiovascular disease. Despite significant advances in cancer therapeuti......

JIF:4.403

Role of non-coding RNA in immune microenvironment and anticancer therapy of gastric cancer

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (12)

Gastric cancer remains one of the cancers with the highest mortality in the world; therefore, it is very important to investigate its pathogenesis to ......

JIF:4.403

Evaluation of EpCAM-specific exosomal lncRNAs as potential diagnostic biomarkers for lung cancer using droplet digital PCR

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (1)

Accumulating evidence demonstrated that long non-coding RNAs (lncRNAs) derived from exosomes had the potential to be diagnostic markers for lung cance......

JIF:4.403

Ziprasidone suppresses pancreatic adenocarcinoma cell proliferation by targeting GOT1 to trigger glutamine metabolism reprogramming

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (4)

Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignant tumor whose effective treatment has not been found. The redox state and proliferative act......

JIF:4.403

mTOR-FABP4 signal is activated in brain arteriovenous malformations in humans

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (9)

Arteriovenous malformations (AVMs) are the most common types of cerebral vascular malformations, which are dynamic lesions with de novo growth potenti......

JIF:4.403

Zinc finger and BTB domain-containing protein 20 aggravates angiotensin II-induced cardiac remodeling via the EGFR-AKT pathway

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (3)

Zinc finger and BTB domain-containing protein 20 (ZBTB20) play an important role in glucose and lipid homeostasis. ZBTB20 was shown to be a crucial pr......

JIF:4.403

Advances in gene therapy for neurogenetic diseases: a brief review

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (3)

Neurogenetic diseases are neurological conditions with a genetic cause (s). There are thousands of neurogenetic diseases, and most of them are incurab......

JIF:4.403

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (5)

An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the ......

JIF:4.403

Progranulin, a moderator of estrogen/estrogen receptor a binding, regulates bone homeostasis through PERK/p-elF2 signaling pathway

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (8)

Under normal conditions, the human body employs the synergistic action of osteoblasts and osteoclasts to maintain a dynamic balance between bone forma......

JIF:4.403

Transcription factor EB inhibits non-alcoholic fatty liver disease through fibroblast growth factor 21

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (11)

We sought to explore the potential role of transcription factor EB (TFEB) in the pathogenesis of the non-alcoholic fatty liver disease (NAFLD). An NAF......

JIF:4.403

Circulating tumor cells in colorectal cancer in the era of precision medicine

期刊: JOURNAL OF MOLECULAR MEDICINE-JMM, 2022; 100 (2)

Colorectal cancer (CRC) is one of the main causes of cancer-related morbidity and mortality across the globe. Although serum biomarkers such as carcin......

JIF:4.403

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