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Knockdown of HCG18 Inhibits Cell Viability, Migration and Invasion in Pediatric Osteosarcoma by Targeting miR-188-5p/FOXC1 Axis

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (9)

Understanding the underlying mechanisms of pediatric osteosarcoma (OS) migration and invasion is important for prognosis and treatment. We tried to me......

LncRNA CCDC144NL-AS1 Serves as a Prognosis Biomarker for Non-small Cell Lung Cancer and Promotes Cellular Function by Targeting miR-490-3p

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (10)

This study revealed the prognostic significance of long non-coding RNA (lncRNA) CCDC144NL-AS1 in NSCLC patients and discussed the effect and mechanism......

Inhibition Sequence of miR-205 Hinders the Cell Proliferation and Migration of Lung Cancer Cells by Regulating PETN-Mediated PI3K/AKT Signal Pathway

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (7)

The aim of this study was to identify the pro-tumor role of miR-205 in patients with lung cancer (LC) on the cell proliferation and migration through ......

Increasing Long-Chain Dicarboxylic Acid Production in Candida tropicalis by Engineering Fatty Transporters

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (6)

Candida tropicalis can metabolize alkanes or fatty acids to produce long-chain dicarboxylic acids (DCAs). Fatty acid transporters located on the cell ......

Survey of Drought-Associated TAWRKY2-D1 Gene Diversity in Bread Wheat and Wheat Relatives

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (10)

Recent advances in plant genomics revealed numerous factors related to drought tolerance, including a family of WRKY transcription factors. The aim of......

MicroRNA miR-29a Inhibits Colon Cancer Progression by Downregulating B7-H3 Expression: Potential Molecular Targets for Colon Cancer Therapy

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (9)

MiR-29a belongs to one of the subtypes of miRNAs known as non-coding single-stranded RNAs and is preferentially expressed in normal tissues. B7-H3, a ......

Development of a miRNA Sensor by an Inducible CRISPR-Cas9 Construct in Ciona Embryogenesis

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (7)

MicroRNAs (miRNAs) regulate multicellular processes and diverse signaling pathways in organisms. The detection of the spatiotemporal expression of miR......

LncRNA NEAT1 Regulates Infantile Pneumonia by Sponging miR-146b

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (8)

This study designed to investigate the potential role of lncRNA NEAT1/miR-146b in infantile pneumonia. In this study, 58 children with pneumonia and 5......

Effect of miR-126 on the Proliferation and Migration of Vascular Smooth Muscle Cells in Aortic Aneurysm Mice Under PI3K/AKT/mTOR Signaling Pathway

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (7)

This paper is to investigate the expression changes of Phosphatidylinositol-3 Kinase (PI3K), protein kinase B (AKT), and Mammalian Target of Rapamycin......

Micro-RNA-338-3p Promotes the Development of Atherosclerosis by Targeting Desmin and Promoting Proliferation

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (9)

Atherosclerosis (AS) is a dynamic and multi-stage process that involves various cells types, such as vascular smooth muscle cells (VSMCs) and molecule......

The Accumulation of Lutein and beta-Carotene and Transcript Profiling of Genes Related to Carotenoids Biosynthesis in Yellow Celery

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (7)

Carotenoids are the general term of natural pigments. The formation of plant color is probably related to the components of carotenoids. As the yellow......

Strategies to Increase the Production of Biosynthetic Riboflavin

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (10)

Riboflavin is widely regarded as an essential nutrient that is involved in biological oxidation in vivo. In addition to preventing and treating acyl-C......

MiR-124-3p Suppresses Prostatic Carcinoma by Targeting PTGS2 Through the AKT/NF-kappa B Pathway

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (7)

MiR-124-3p had shown its tumor-regulatory properties in different cancers, but its potential roles in prostatic carcinoma had not been clearly underst......

Ubiquitin-Specific Peptidase 5 is Involved in the Proliferation of Trophoblast Cells by Regulating Wnt/beta-Catenin Signaling

期刊: MOLECULAR BIOTECHNOLOGY, 2021; 63 (8)

Preeclampsia (PE) is a pathologic condition in pregnant women which accounts for the inhibition of proliferation, migration and invasion of trophoblas......

Purification and Characterization of (2R,3R)-2,3-Butanediol Dehydrogenase of the Human Pathogen Neisseria gonorrhoeae FA1090 Produced in Escherichia coli

期刊: MOLECULAR BIOTECHNOLOGY, ; ()

2,3-Butanediol dehydrogenase (BDH), also known as acetoin/diacetyl reductase, is a pivotal enzyme for the formation of 2,3-butanediol (2,3-BD), a chir......

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