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Cox regression analysis for distorted covariates with an unknown distortion function

期刊: BIOMETRICAL JOURNAL, ; ()

We study inference for censored survival data where some covariates are distorted by some unknown functions of an observable confounding variable in a......

D-optimal designs of mean-covariance models for longitudinal data

期刊: BIOMETRICAL JOURNAL, ; ()

Longitudinal data analysis has been very common in various fields. It is important in longitudinal studies to choose appropriate numbers of subjects a......

Smoothed empirical likelihood inference for ROC curve in the presence of missing biomarker values

期刊: BIOMETRICAL JOURNAL, 2020; 62 (4)

This paper considers statistical inference for the receiver operating characteristic (ROC) curve in the presence of missing biomarker values by utiliz......

IV estimation without distributional assumptions

期刊: BIOMETRICAL JOURNAL, 2020; 62 (3)

It is widely known that Instrumental Variable (IV) estimation allows the researcher to estimate causal effects between an exposure and an outcome even......

A regularized estimation approach for case-cohort periodic follow-up studies with an application to HIV vaccine trials

期刊: BIOMETRICAL JOURNAL, 2020; 62 (5)

This paper discusses regression analysis of the failure time data arising from case-cohort periodic follow-up studies, and one feature of such data, w......

Bayesian interval mapping of count trait loci based on zero-inflated generalized Poisson regression model

期刊: BIOMETRICAL JOURNAL, 2020; 62 (6)

Count phenotypes with excessive zeros are often observed in the biological world. Researchers have studied many statistical methods for mapping the qu......

Parametric mode regression for bounded responses

期刊: BIOMETRICAL JOURNAL, 2020; 62 (7)

We propose new parametric frameworks of regression analysis with the conditional mode of a bounded response as the focal point of interest. Covariate ......

Nonparametric screening and feature selection for ultrahigh-dimensional Case II interval-censored failure time data

期刊: BIOMETRICAL JOURNAL, 2020; 62 (8)

For the analysis of ultrahigh-dimensional data, the first step is often to perform screening and feature selection to effectively reduce the dimension......

Tuning model parameters in class-imbalanced learning with precision-recall curve

期刊: BIOMETRICAL JOURNAL, 2019; 61 (3)

An issue for class-imbalanced learning is what assessment metric should be employed. So far, precision-recall curve (PRC) as a metric is rarely used i......

JIF:1.25

Multistate modeling and simulation of patient trajectories after allogeneic hematopoietic stem cell transplantation to inform drug development

期刊: BIOMETRICAL JOURNAL, 2019; 61 (5)

We present a case study for developing clinical trial scenarios in a complex progressive disease with multiple events of interest. The idea is to firs......

JIF:1.25

Joint mean-covariance random effect model for longitudinal data

期刊: BIOMETRICAL JOURNAL, 2020; 62 (1)

In this paper, we consider the inherent association between mean and covariance in the joint mean-covariance modeling and propose a joint mean-covaria......

On construction of single-arm two-stage designs with consideration of both response and toxicity

期刊: BIOMETRICAL JOURNAL, 2019; 61 (6)

When establishing a treatment in clinical trials, it is important to evaluate both effectiveness and toxicity. In phase II clinical trials, multinomia......

JIF:1.25

Joint regression analysis for survival data in the presence of two sets of semi-competing risks

期刊: BIOMETRICAL JOURNAL, 2019; 61 (6)

In many clinical trials, multiple time-to-event endpoints including the primary endpoint (e.g., time to death) and secondary endpoints (e.g., progress......

JIF:1.25

A new multivariate zero-adjusted Poisson model with applications to biomedicine

期刊: BIOMETRICAL JOURNAL, 2019; 61 (6)

Recently, although advances were made on modeling multivariate count data, existing models really has several limitations: (i) The multivariate Poisso......

JIF:1.25

Two-stage orthogonality based estimation for semiparametric varying-coefficient models and its applications in analyzing AIDS data

期刊: BIOMETRICAL JOURNAL, 2018; 60 (1)

Semiparametric smoothing methods are usually used to model longitudinal data, and the interest is to improve efficiency for regression coefficients. T......

JIF:1.25

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