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The Contribution of PDCD6 Polymorphisms to Oral Cancer Risk

期刊: CANCER GENOMICS & PROTEOMICS, 2022; 19 (4)

Background/Aim: Programmed cell death 6 (PDCD6) is up-regulated and highly expressed in early apoptotic cells. In several types of cancer, such as cer......

JIF:3.351

Novel Contribution of Long Non-coding RNA MEG3 Genotype to Prediction of Childhood Leukemia Risk

期刊: CANCER GENOMICS & PROTEOMICS, 2022; 19 (1)

Background/Aim: Acute lymphoblastic leukemia (ALL) is frequent among children. Few studies have researched the relationship between maternally express......

JIF:3.351

The Application of Bayesian Methods in Cancer Prognosis and Prediction

期刊: CANCER GENOMICS & PROTEOMICS, 2022; 19 (1)

With the development of high-throughput biological techniques, high-dimensional omics data have emerged. These molecular data provide a solid foundati......

JIF:3.351

beta-Arrestin2 Inhibits the Apoptosis and Facilitates the Proliferation of Fibroblast-like Synoviocytes in Diffuse-type Tenosynovial Giant Cell Tumor

期刊: CANCER GENOMICS & PROTEOMICS, 2021; 18 (3)

Background/Aim: Diffuse-type tenosynovial giant cell tumor (TGCT) is a rare benign proliferative synovial neoplasm of uncertain etiology, and the effi......

Efficacy of YAP1-gene Knockdown to Inhibit Alveolar-Epithelial-Cell Senescence and Alleviate Idiopathic Pulmonary Fibrosis (IPF)

期刊: CANCER GENOMICS & PROTEOMICS, 2021; 18 (3)

Background/Aim: The prevalence of idiopathic pulmonary fibrosis (IPF) increases with age and is associated with senescence of alveolar epithelial cell......

Contribution of Matrix Metalloproteinase-1 Genotypes to Colorectal Cancer in Taiwan

期刊: CANCER GENOMICS & PROTEOMICS, 2021; 18 (3)

Background/Aim: Matrix metalloproteinase-1 is responsible for extracellular matrix regulation, and its genetic role in colorectal cancer (CRC) is uncl......

Deep Dive on the Proteome of Human Body Fluids: A Valuable Data Resource for Biomarker Discovery

期刊: CANCER GENOMICS & PROTEOMICS, 2021; 18 (4)

Background/Aim: Body fluids are considered to be a rich source of disease biomarkers. Proteins in many body fluids have potential clinical application......

Interaction of DNA Repair Gene XPC With Smoking and Betel Quid Chewing Behaviors of Oral Cancer

期刊: CANCER GENOMICS & PROTEOMICS, 2021; 18 (3)

Background/Aim: Xeroderma pigmentosum complementation group C (XPC) is reported to play important roles in DNA integrity and genomic instability, howe......

PTBP1 Genetic Variants Affect the Clinical Response to Androgen-deprivation Therapy in Patients With Prostate Cancer

期刊: CANCER GENOMICS & PROTEOMICS, 2021; 18 (3)

Background/Aim: Heterogeneous nuclear ribonucleoproteins (hnRNPs) contribute to multiple cellular functions including RNA splicing, stabilization, tra......

NONO Is a Negative Regulator of SOX2 Promoter

期刊: CANCER GENOMICS & PROTEOMICS, 2020; 17 (4)

Background/Aim: Sex determining region Y (SRY)-box 2 (SOX2) is a transcription factor essential for the maintenance of proliferation and self-renewal ......

The Significant Interaction of Excision Repair Cross-complementing Group 1 Genotypes and Smoking to Lung Cancer Risk

期刊: CANCER GENOMICS & PROTEOMICS, 2020; 17 (5)

Background: The study aims to evaluate the contribution of excision repair cross-complementing group 1 (ERCC1), which plays an important role in genom......

Genetic Analysis Identifies the Role of HLF in Renal Cell Carcinoma

期刊: CANCER GENOMICS & PROTEOMICS, 2020; 17 (6)

Background/Aim: Circadian rhythm is an internal clock that regulates the cycles of many biological functions. Epidemiological studies have linked aber......

The Clinical Relevance of Frequent Germline Genetic Variants Detected by Targeted Sequencing in Patients With Rectal Adenocarcinoma (READ)

期刊: CANCER GENOMICS & PROTEOMICS, 2020; 17 (3)

Background: The progression of colorectal cancer (CRC) mainly stems from the occurrence of somatic mutation. However, there is little information that......

Therapeutic Efficacy Evaluation of Pegylated Liposome Encapsulated With Vinorelbine Plus In-111 Repeated Treatments in Human Colorectal Carcinoma With Multimodalities of Molecular Imaging

期刊: CANCER GENOMICS & PROTEOMICS, 2020; 17 (1)

Background/Aim: In precision therapy, liposomal encapsulated chemotherapeutic drugs have been developed to treat cancers by achieving higher drug accu......

Increased Expression of Gremlin 1 Promotes Proliferation and Epithelial Mesenchymal Transition in Gastric Cancer Cells and Correlates With Poor Prognosis of Patients With Gastric Cancer

期刊: CANCER GENOMICS & PROTEOMICS, 2020; 17 (1)

Background/Aim: Gremlin1 (GREM1) plays an important role in certain malignancies by antagonising bone morphogenetic proteins and regulating angiogenes......

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