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Ibrutinib in Advanced Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Lower Risk of Hepatitis B Virus Reactivation

期刊: ACTA HAEMATOLOGICA, 2022; 145 (1)

Introduction: Therapy of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with drugs such as ibrutinib and rituximab is often associa......

JIF:1.497

A Novel ANK1 Mutation in a Neonatal Hereditary Spherocytosis Case: Diagnostic Challenges and Familial Genetic Analysis

期刊: ACTA HAEMATOLOGICA, 2022; 145 (6)

Hereditary spherocytosis (HS) is a congenital disease in which erythrocyte membranes are abnormal, with ANK1 defects as the main cause. The diagnosis ......

JIF:1.497

Preliminary Study on Apoptotic Proteins in Platelet from Adult Patients with Chronic Immune Thrombocytopenic Purpura

期刊: ACTA HAEMATOLOGICA, 2022; 145 (3)

Background: Adult chronic idiopathic thrombocytopenic purpura (ITP) is a chronic and usually lifelong hemorrhagic disorder in which enhanced platelet ......

JIF:1.497

Myeloid Neoplasm with PCM1-PDGFRB Transcript Responded to Low-Dose Imatinib: One Case Report with Literature Review

期刊: ACTA HAEMATOLOGICA, 2022; 145 (5)

Through an RNA-seq analysis of an adult patient with unclassifiable myelodysplastic/myeloproliferative neoplasms (MDS/MPN-U), we identified a rare PDG......

JIF:1.497

A Gene Signature Comprising Seven Pyroptosis Related Genes Predicts Prognosis in Pediatric Patients with Acute Myeloid Leukemia

期刊: ACTA HAEMATOLOGICA, 2022; 145 (6)

Introduction: The aim of the study was to construct a pyroptosis-related risk score (RS) model for the prognosis of acute myeloid leukemia (AML). Meth......

JIF:1.497

Small RNA Sequencing Reveals Exosomal miRNAs as Unique Feature Markers in Unprovoked Venous Thromboembolism

期刊: ACTA HAEMATOLOGICA, 2022; 145 (5)

Introduction: Venous thromboembolism (VTE) is a common cardiovascular disease. MicroRNAs (miRNAs) play a key role in VTE; however, the role of exosoma......

JIF:1.497

Detection and Gene Mutation Analysis of Three Variations in Two Unrelated Chinese Hereditary Coagulation Factor XI Deficiency Families

期刊: ACTA HAEMATOLOGICA, 2022; 145 (6)

Introduction: Three variations including a novel F11 gene variation were detected in two unrelated Chinese families with coagulation factor XI deficie......

JIF:1.497

STAT3 Promotes Cell Proliferation by Potentiating the CCL4 Transcriptional Activity in Diffuse Large B-Cell Lymphoma

期刊: ACTA HAEMATOLOGICA, 2022; 145 (4)

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor and a candidate therapeutic option for human cancers. However, th......

JIF:1.497

Chemotherapy or Allogeneic Stem Cell Transplantation as Salvage Therapy for Patients with Refractory Acute Myeloid Leukemia: A Multicenter Analysis

期刊: ACTA HAEMATOLOGICA, 2022; 145 (4)

Introduction: The overall outcome of patients with refractory AML (rAML) remains poor. Though allogeneic hematopoietic stem cell transplantation (allo......

JIF:1.497

MiR-199a-3p Overexpression Suppressed Cell Proliferation and Sensitized Chronic Myeloid Leukaemia Cells to Imatinib by Inhibiting mTOR Signalling

期刊: ACTA HAEMATOLOGICA, 2022; 145 (5)

Introduction: Chronic myeloid leukaemia (CML) is a myeloproliferative neoplasm characterized by constitutive activity of the tyrosine kinase BCR-ABL1.......

JIF:1.497

The Mechanistic Effects and Clinical Applications of Various Derived Mesenchymal Stem Cells in Immune Thrombocytopenia

期刊: ACTA HAEMATOLOGICA, 2022; 145 (1)

Immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by persistent thrombocytopenia resulting from increased platelet destru......

JIF:1.497

Efficacy of Individualized Preventive Treatment of Patients with Severe Hemophilia A Guided by Multiple Clinical Parameters and Pharmacokinetics

期刊: ACTA HAEMATOLOGICA, 2022; 145 (4)

Objective: The objective of the study was to investigate the effect of multiple clinical parameters (age, weight, blood types, and bleeding types) on ......

JIF:1.497

Using Circ-ANAPC7 as a Novel Type of Biomarker in the Monitoring of Acute Myeloid Leukemia

期刊: ACTA HAEMATOLOGICA, 2022; 145 (2)

Introduction: Circular RNAs (circRNAs) are a novel class of RNAs which occupy gene expression at the transcriptional or post-transcriptional level, in......

JIF:1.497

Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Blood Safety

期刊: ACTA HAEMATOLOGICA, 2022; 145 (4)

Since the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it has spread rapidly around the world and caused a serious global......

JIF:1.497

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